The essential medicinal chemistry of curcumin: miniperspective

KM Nelson, JL Dahlin, J Bisson, J Graham… - Journal of medicinal …, 2017 - ACS Publications
Curcumin is a constituent (up to∼ 5%) of the traditional medicine known as turmeric. Interest
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …

[HTML][HTML] Phytochemistry and pharmacological activity of the genus artemisia

D Bisht, D Kumar, D Kumar, K Dua… - Archives of Pharmacal …, 2021 - Springer
Artemisia and its allied species have been employed for conventional medicine in the
Northern temperate regions of North America, Europe, and Asia for the treatments of …

[HTML][HTML] Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium)

GES Batiha, A Olatunde, A El-Mleeh, HF Hetta… - Antibiotics, 2020 - mdpi.com
Plants have been used since ancient times to cure certain infectious diseases, and some of
them are now standard treatments for several diseases. Due to the side effects and …

[HTML][HTML] Medicinal and mechanistic overview of artemisinin in the treatment of human diseases

AM Posadino, R Giordo, G Pintus… - Biomedicine & …, 2023 - Elsevier
Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has
been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial …

[HTML][HTML] Insights into CYP2B6-mediated drug–drug interactions

WD Hedrich, HE Hassan, H Wang - Acta Pharmaceutica Sinica B, 2016 - Elsevier
Mounting evidence demonstrates that CYP2B6 plays a much larger role in human drug
metabolism than was previously believed. The discovery of multiple important substrates of …

Recent pharmacological advances in the repurposing of artemisinin drugs

Y Meng, N Ma, H Lyu, YK Wong… - Medicinal research …, 2021 - Wiley Online Library
Artemisinins are a family of sesquiterpene lactones originally derived from the sweet
wormwood (Artemisia annua). Beyond their well‐characterized role as frontline antimalarial …

Research progress on nanotechnology for delivery of active ingredients from traditional Chinese medicines

L Qiao, M Han, S Gao, X Shao, X Wang… - Journal of Materials …, 2020 - pubs.rsc.org
There is growing acceptance of traditional Chinese medicines (TCMs) as potential sources
of clinical agents based on the demonstrated efficacies of numerous bioactive compounds …

[HTML][HTML] Pharmacological Modulators of Autophagy as a Potential Strategy for the Treatment of COVID-19

GJS Pereira, AHFF Leão, AG Erustes… - International Journal of …, 2021 - mdpi.com
The family of coronaviruses (CoVs) uses the autophagy machinery of host cells to promote
their growth and replication; thus, this process stands out as a potential target to combat …

Protective effect and possible mechanisms of Artemisinin and its derivatives for diabetic nephropathy: a systematic review and meta‐analysis in animal models

H Feng, T Wu, Q Zhou, H Li, T Liu… - … Medicine and Cellular …, 2022 - Wiley Online Library
Background. Artemisinin and its derivatives have potential antidiabetic effects. There is no
evaluation of reported studies in the literature on the treatment of diabetic nephropathy (DN) …

[HTML][HTML] Synthesis of five-and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products

AO Terent'ev, DA Borisov, VA Vil… - Beilstein Journal of …, 2014 - beilstein-journals.org
The present review describes the current status of synthetic five and six-membered cyclic
peroxides such as 1, 2-dioxolanes, 1, 2, 4-trioxolanes (ozonides), 1, 2-dioxanes, 1, 2 …