Systemic lupus erythematosus: new diagnostic and therapeutic approaches

S Lazar, JM Kahlenberg - Annual review of medicine, 2023 - annualreviews.org
Systemic lupus erythematosus (SLE) is a devastating autoimmune disease that can result in
substantial morbidity and mortality. Diagnosis and treatment of SLE are clinical challenges …

New insights into the role of antinuclear antibodies in systemic lupus erythematosus

DS Pisetsky, PE Lipsky - Nature Reviews Rheumatology, 2020 - nature.com
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by
antinuclear antibodies (ANAs) that form immune complexes that mediate pathogenesis by …

[HTML][HTML] Increasing prevalence of antinuclear antibodies in the United States

GE Dinse, CG Parks, CR Weinberg, CA Co… - Arthritis & …, 2020 - ncbi.nlm.nih.gov
Objective. Growing evidence suggests increasing frequencies of autoimmunity and certain
autoimmune diseases, but findings are limited by the lack of systematic data and evolving …

Understanding and interpreting antinuclear antibody tests in systemic rheumatic diseases

X Bossuyt, E De Langhe, MO Borghi… - Nature Reviews …, 2020 - nature.com
Antinuclear antibodies (ANAs) are valuable laboratory markers to screen for and support the
diagnosis of various rheumatic diseases (known as ANA-associated rheumatic diseases) …

Systemic sclerosis-specific antibodies: novel and classical biomarkers

I Cavazzana, T Vojinovic, P Airo', M Fredi… - Clinical Reviews in …, 2023 - Springer
Disease-specific autoantibodies are considered the most important biomarkers for systemic
sclerosis (SSc), due to their ability to stratify patients with different severity and prognosis …

239th ENMC international workshop: classification of dermatomyositis, Amsterdam, the Netherlands, 14–16 December 2018

AL Mammen, Y Allenbach, W Stenzel… - Neuromuscular …, 2020 - Elsevier
Idiopathic inflammatory myopathies (IIM) are a heterogenous family of diseases that can
affect the muscles, skin, lungs, and joints. There have been prior attempts to classify IIMs …

Clinical and immunological biomarkers for systemic lupus erythematosus

H Yu, Y Nagafuchi, K Fujio - Biomolecules, 2021 - mdpi.com
Systemic lupus erythematosus (SLE) is characterized by immune system dysfunction and is
clinically heterogeneous, exhibiting renal, dermatological, neuropsychiatric, and …

Artificial intelligence and deep learning for rheumatologists

C McMaster, A Bird, DFL Liew… - Arthritis & …, 2022 - Wiley Online Library
Deep learning has emerged as the leading method in machine learning, spawning a rapidly
growing field of academic research and commercial applications across medicine. Deep …

Antinuclear autoantibodies in health: autoimmunity is not a synonym of autoimmune disease

IA Pashnina, IM Krivolapova, TV Fedotkina… - Antibodies, 2021 - mdpi.com
The incidence of autoimmune diseases is increasing. Antinuclear antibody (ANA) testing is a
critical tool for their diagnosis. However, ANA prevalence in healthy persons has increased …

Scleromyositis: a distinct novel entity within the systemic sclerosis and autoimmune myositis spectrum. Implications for care and pathogenesis

M Giannini, B Ellezam, V Leclair, F Lefebvre… - Frontiers in …, 2023 - frontiersin.org
Systemic sclerosis and autoimmune myositis are both associated with decreased quality of
life and increased mortality. Their prognosis and management largely depend on the …