Exploring the out of sight antigens of SARS-CoV-2 to design a candidate multi-epitope vaccine by utilizing immunoinformatics approaches
SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health
is facing its devastating outbreak. However, there is no vaccine available against this virus …
is facing its devastating outbreak. However, there is no vaccine available against this virus …
Immunoinformatics-based potential multi-peptide vaccine designing against Jamestown Canyon Virus (JCV) capable of eliciting cellular and humoral immune …
M Shahab, S Aiman, A Alshammari, AF Alasmari… - International Journal of …, 2023 - Elsevier
Jamestown Canyon virus (JCV) is a deadly viral infection transmitted by various mosquito
species. This mosquito-borne virus belongs to Bunyaviridae family, posing a high public …
species. This mosquito-borne virus belongs to Bunyaviridae family, posing a high public …
In-silico design of an immunoinformatics based multi-epitope vaccine against Leishmania donovani
Abstract Background Visceral Leishmaniasis (VL) is a fatal vector-borne parasitic disorder
occurring mainly in tropical and subtropical regions. VL falls under the category of neglected …
occurring mainly in tropical and subtropical regions. VL falls under the category of neglected …
A candidate vaccine for human visceral leishmaniasis based on a specific T cell epitope-containing chimeric protein protects mice against Leishmania infantum …
DP Lage, PAF Ribeiro, DS Dias, DVC Mendonça… - npj Vaccines, 2020 - nature.com
Leishmaniases are neglected diseases caused by infection with Leishmania parasites and
there are currently no prophylactic vaccines. In this study, we designed in silico a synthetic …
there are currently no prophylactic vaccines. In this study, we designed in silico a synthetic …
Immunoinformatics-driven in silico vaccine design for Nipah virus (NPV): Integrating machine learning and computational epitope prediction
The Nipah virus (NPV) is a highly lethal virus, known for its significant fatality rate. The virus
initially originated in Malaysia in 1998 and later led to outbreaks in nearby countries such as …
initially originated in Malaysia in 1998 and later led to outbreaks in nearby countries such as …
An immunoinformatic approach driven by experimental proteomics: in silico design of a subunit candidate vaccine targeting secretory proteins of Leishmania donovani …
Background Visceral leishmaniasis (VL) caused by dimorphic Leishmania species is a
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …
parasitic disease with high socioeconomic burden in endemic areas worldwide. Sustaining …
A cutting-edge immunoinformatics approach for design of multi-epitope oral vaccine against dreadful human malaria
Human malaria is a pathogenic disease mainly caused by Plasmodium falciparum, which
was responsible for about 405,000 deaths globally in the year 2018. To date, several …
was responsible for about 405,000 deaths globally in the year 2018. To date, several …
Prediction of an immunogenic peptide ensemble and multi-subunit vaccine for Visceral leishmaniasis using bioinformatics approaches
Visceral Leishmaniasis (VL) is a neglected tropical disease of public health importance in
the Indian subcontinent. Despite consistent elimination initiatives, the disease has not yet …
the Indian subcontinent. Despite consistent elimination initiatives, the disease has not yet …
In silico and immunoinformatics based multiepitope subunit vaccine design for protection against visceral leishmaniasis
D Bhowmik, A Bhuyan, S Gunalan… - Journal of …, 2023 - Taylor & Francis
Visceral leishmaniasis (VL) is a vector-borne neglected tropical protozoan disease with high
fatality and no certified vaccine. Conventional vaccine preparation is challenging and …
fatality and no certified vaccine. Conventional vaccine preparation is challenging and …
Prenylated notoamide-type alkaloids isolated from the fungus Aspergillus sclerotiorum and their inhibition of NLRP3 inflammasome activation and antibacterial …
Q Meng, X Guo, J Wu, D Liu, Y Gu, J Huang, A Fan… - Phytochemistry, 2022 - Elsevier
Notoamides are a family of prenylated indole alkaloids with unusual ring systems and
possessing a range of significant pharmaceutical activities. Based on LC-MS/MS and …
possessing a range of significant pharmaceutical activities. Based on LC-MS/MS and …