Choriocapillaris: fundamentals and advancements
The choriocapillaris is the innermost structure of the choroid that directly nourishes the
retinal pigment epithelium and photoreceptors. This article provides an overview of its …
retinal pigment epithelium and photoreceptors. This article provides an overview of its …
Development of the hyaloid, choroidal and retinal vasculatures in the fetal human eye
The development of the ocular vasculatures is perfectly synchronized to provide the
nutritional and oxygen requirements of the forming human eye. The fetal vasculature of …
nutritional and oxygen requirements of the forming human eye. The fetal vasculature of …
Exploring the intracrine functions of VEGF-A
S Wiszniak, Q Schwarz - Biomolecules, 2021 - mdpi.com
Vascular endothelial growth factor A (VEGF-A or VEGF) is a highly conserved secreted
signalling protein best known for its roles in vascular development and angiogenesis. Many …
signalling protein best known for its roles in vascular development and angiogenesis. Many …
[HTML][HTML] Human retinal secretome: A cross-link between mesenchymal and retinal cells
L Donato, C Scimone, S Alibrandi… - World Journal of Stem …, 2023 - ncbi.nlm.nih.gov
In recent years, mesenchymal stem cells (MSC) have been considered the most effective
source for regenerative medicine, especially due to released soluble paracrine bioactive …
source for regenerative medicine, especially due to released soluble paracrine bioactive …
Detection of VEGF-Axxxb Isoforms in Human Tissues
DO Bates, A Mavrou, Y Qiu, JG Carter… - PloS one, 2013 - journals.plos.org
Vascular Endothelial Growth Factor-A (VEGF-A) can be generated as multiple isoforms by
alternative splicing. Two families of isoforms have been described in humans, pro …
alternative splicing. Two families of isoforms have been described in humans, pro …
The role of VEGF165b in pathophysiology
M Peiris-Pagès - Cell adhesion & migration, 2012 - Taylor & Francis
Anti-angiogenic vascular endothelial growth factor A (VEGF) 165b and pro-angiogenic
VEGF165 are generated from the same transcript, and their relative amounts are dependent …
VEGF165 are generated from the same transcript, and their relative amounts are dependent …
[HTML][HTML] Short hairpin RNA-mediated knockdown of VEGFA in Müller cells reduces intravitreal neovascularization in a rat model of retinopathy of prematurity
H Wang, GW Smith, Z Yang, Y Jiang… - The American journal of …, 2013 - Elsevier
Vascular endothelial growth factor (VEGF) A is implicated in aberrant angiogenesis and
intravitreous neovascularization (IVNV) in retinopathy of prematurity (ROP). However …
intravitreous neovascularization (IVNV) in retinopathy of prematurity (ROP). However …
SRPK1 inhibition modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy of prematurity
MVR Gammons, AD Dick, SJ Harper… - … & visual science, 2013 - iovs.arvojournals.org
Purpose.: Wetested the hypothesis that recombinant human VEGF-A 165 b and the serine
arginine protein kinase (SRPK) inhibitor, SRPIN340, which controls splicing of the VEGF-A …
arginine protein kinase (SRPK) inhibitor, SRPIN340, which controls splicing of the VEGF-A …
WNT5A regulates adipose tissue angiogenesis via antiangiogenic VEGF-A165b in obese humans
Experimental studies have suggested that Wingless-related integration site 5A (WNT5A) is a
proinflammatory secreted protein that is associated with metabolic dysfunction in obesity …
proinflammatory secreted protein that is associated with metabolic dysfunction in obesity …
Integrative single‐cell transcriptomics and epigenomics mapping of the fetal retina developmental dynamics
R Li, J Liu, P Yi, X Yang, J Chen, C Zhao… - Advanced …, 2023 - Wiley Online Library
The underlying mechanisms that determine gene expression and chromatin accessibility in
retinogenesis are poorly understood. Herein, single‐cell RNA sequencing and single‐cell …
retinogenesis are poorly understood. Herein, single‐cell RNA sequencing and single‐cell …