Salmonella enterica serovar Typhimurium is a primary enteric pathogen infecting both
humans and animals. Infection begins with the ingestion of contaminated food or water so …

Salmonella enterica serovars cause severe disease in humans, such as gastroenteritis and
typhoid fever. The bacteria are able to invade and replicate within host cells, including …

Salmonella enterica serovar Typhimurium is arguably the world's best-understood bacterial
pathogen. However, crucial details about the genetic programs used by the bacterium to …

In bacteria, two-component systems (TCS) are widely used signal transduction devices
which are engaged in a multitude of gene regulatory systems that respond to changing …

Although it has become routine to consider DNA in terms of its role as a carrier of genetic
information, it is also an important contributor to the control of gene expression. This …

Salmonella enterica invades the intestinal epithelium of the host using a type III secretion
system encoded on Salmonella pathogenicity island 1 (SPI1). The bacteria integrate …

The Salmonella Pathogenicity Island-2 (ie SPI-2) encodes a unique type III secretion system
that delivers effector proteins from the Salmonella-containing vacuole (SCV) into the host …

Spi/Ssa is a unique type three secretion system that functions exclusively when Salmonella
enterica is inside eukaryotic cells. Expression of the Spi/Ssa system and its secreted …

Unlike eukaryotes, bacteria undergo large changes in osmolality and cytoplasmic pH. It has
been described that during acid stress, bacteria internal pH promptly acidifies, followed by …

Bacteria survive and respond to diverse environmental conditions and during infection
inside the host by systematic regulation of stress response genes. E. coli and S …