Increasing interest in studying the role of vitamin D in cancer has been provided by the
scientific literature during the last years, although mixed results have been reported. Vitamin …

Vitamin D deficiency is a global health problem due to its high prevalence and its negative
consequences on musculoskeletal and extra-skeletal health. In our comparative review of …

Abstract Background Although vitamin D (VD) is chemoprotective and enhances 5-
fluorouracil (5-FU) cytotoxicity against colorectal cancer (CRC), little is known about its …

Fluorouracil (5-FU) is an anticancer drug that is most frequently used to treat colorectal
cancer (CRC) patients, but unfortunately it shows limited efficacy. We recently demonstrated …

Zinc, ω-3 polyunsaturated fatty acids (PUFAs) and vitamin D are essential nutrients for
health, maturation and general wellbeing. Extensive literature searches have revealed the …

Background There is an obvious correlation between ulcerative colitis and colorectal cancer,
and the risk of colorectal cancer in patients with ulcerative colitis is increasing. Therefore, the …

The diverse effects of 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3), the bio-active form of
vitamin D, on cancer cell metabolism and proliferation has made it an interesting candidate …

Glycolysis plays a vital role in the development and progression of tumors. Inhibiting
glycolysis via smart and safe methods serves as a promising target for cancer therapy. Here …

Vitamin D supplementation and vitamin D deficiency are common in clinical experience and
in daily life. Vitamin D not only promotes calcium absorption and immune regulation, but …

Combining natural products as co-adjuvants in 5-fluorouracil (5-FU) chemotherapy might
enhance the effectiveness of 5-FU by avoiding a high dosage and/or reducing treatment …