Chromatin remodeler Activity-Dependent Neuroprotective Protein (ADNP) contributes to syndromic autism
CP D'Incal, KE Van Rossem, K De Man, A Konings… - Clinical …, 2023 - Springer
Background Individuals affected with autism often suffer additional co-morbidities such as
intellectual disability. The genes contributing to autism cluster on a relatively limited number …
intellectual disability. The genes contributing to autism cluster on a relatively limited number …
Rho signaling in synaptic plasticity, memory, and brain disorders
Memory impairments are associated with many brain disorders such as autism, Alzheimer's
disease, and depression. Forming memories involves modifications of synaptic transmission …
disease, and depression. Forming memories involves modifications of synaptic transmission …
Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations
Abstract Autism Spectrum Disorder (ASD) is characterized mainly by social and sensory-
motor abnormal and repetitive behavior patterns. Over hundreds of genes and thousands of …
motor abnormal and repetitive behavior patterns. Over hundreds of genes and thousands of …
Neurons: the interplay between cytoskeleton, ion channels/transporters and mitochondria
Neurons are permanent cells whose key feature is information transmission via chemical
and electrical signals. Therefore, a finely tuned homeostasis is necessary to maintain …
and electrical signals. Therefore, a finely tuned homeostasis is necessary to maintain …
EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons
SS Parker, KT Ly, AD Grant, J Sweetland… - Journal of Cell …, 2023 - rupress.org
Dendritic spines are the postsynaptic compartment of a neuronal synapse and are critical for
synaptic connectivity and plasticity. A developmental precursor to dendritic spines, dendritic …
synaptic connectivity and plasticity. A developmental precursor to dendritic spines, dendritic …
Changes in the number and morphology of dendritic spines in the hippocampus and prefrontal cortex of the C58/J mouse model of autism
I Barón-Mendoza, E Maqueda-Martínez… - Frontiers in Cellular …, 2021 - frontiersin.org
Autism spectrum disorder (ASD) has a broad range of neurobiological characteristics,
including alterations in dendritic spines, where approximately 90% of excitatory synapses …
including alterations in dendritic spines, where approximately 90% of excitatory synapses …
[HTML][HTML] PCDH12 loss results in premature neuronal differentiation and impeded migration in a cortical organoid model
J Rakotomamonjy, L Rylaarsdam, L Fares-Taie… - Cell reports, 2023 - cell.com
Protocadherins (PCDHs) are cell adhesion molecules that regulate many essential
neurodevelopmental processes related to neuronal maturation, dendritic arbor formation …
neurodevelopmental processes related to neuronal maturation, dendritic arbor formation …
The hidden side of NCAM family: NCAM2, a key cytoskeleton organization molecule regulating multiple neural functions
A Parcerisas, A Ortega-Gascó, L Pujadas… - International Journal of …, 2021 - mdpi.com
Although it has been over 20 years since Neural Cell Adhesion Molecule 2 (NCAM2) was
identified as the second member of the NCAM family with a high expression in the nervous …
identified as the second member of the NCAM family with a high expression in the nervous …
Mechanical roles of F-actin in the differentiation of stem cells: a review
In the development and differentiation of stem cells, mechanical forces associated with
filamentous actin (F-actin) play a crucial role. The present review aims to reveal the …
filamentous actin (F-actin) play a crucial role. The present review aims to reveal the …
Different functional connectivity optimal frequency in autism compared with healthy controls and the relationship with social communication deficits: evidence from …
Studies have reported that different brain regions/connections possess distinct frequency
properties, which are related to brain function. Previous studies have proposed altered brain …
properties, which are related to brain function. Previous studies have proposed altered brain …