Diet is a critical element determining human health and diseases, and unbalanced food
habits are major risk factors for the development of obesity and related metabolic disorders …

Epigenetic alterations and metabolic dysfunction are two hallmarks of aging. However, the
mechanism of how their interaction regulates aging, particularly in mammals, remains …

Aims The aim of this study was to systematically review the literature for evidence of the
effect of a high-fat diet (HFD) on the onset or progression of osteoarthritis (OA) in mice …

Individually, metabolic variations can significantly influence predisposition to obesity in the
form of the obesity-prone (super-responders) and obesity-resistant (non-responders) …

Prenatal alcohol exposure (PAE) affects at least 10% of newborns globally and leads to the
development of fetal alcohol spectrum disorders (FASDs). Despite its high incidence, there …

Obesity is characterized with high heterogeneity due to genetic abnormality, energy
imbalance, gut dysbiosis, or a combination of all three. Obesity-prone (OP) and-resistant …

Obesogenic diets increase body weight and cause insulin resistance (IR), however, the
association of these changes with the main macronutrient in the diet remains to be …

The aim of this study was to investigate certain parameters regarding the maternal-fetal
outcomes in a diet-induced obesity model. Obese, glucose-intolerant females who were …

Resistance to high-fat diet-induced obesity (DIR) has been observed in mice fed a high-fat
diet and may provide a potential approach for anti-obesity drug discovery. However, the …

Epigenetic alterations and metabolic dysfunction are two hallmarks of aging. However, the
mechanism of how their interaction regulates aging, particularly in mammals, remains …