Exercise is the real polypill

C Fiuza-Luces, N Garatachea, NA Berger… - Physiology, 2013 - journals.physiology.org
The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …

The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors

JF Thayer, SS Yamamoto, JF Brosschot - International journal of cardiology, 2010 - Elsevier
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. The
understanding of the risk factors for CVD may yield important insights into the prevention …

Brain stimulation modulates the autonomic nervous system, rating of perceived exertion and performance during maximal exercise

AH Okano, EB Fontes, RA Montenegro… - British journal of sports …, 2015 - bjsm.bmj.com
Background The temporal and insular cortex (TC, IC) have been associated with autonomic
nervous system (ANS) control and the awareness of emotional feelings from the body …

Self-reported experiences of everyday discrimination are associated with elevated C-reactive protein levels in older African-American adults

TT Lewis, AE Aiello, S Leurgans, J Kelly… - Brain, behavior, and …, 2010 - Elsevier
Self-reported experiences of “everyday” discrimination have been linked to indices of
cardiovascular disease and overall mortality and findings have been particularly …

Cardiac origins of the postural orthostatic tachycardia syndrome

Q Fu, TB VanGundy, MM Galbreath, S Shibata… - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to test the hypothesis that a small heart coupled
with reduced blood volume contributes to the postural orthostatic tachycardia syndrome …

Exercise and non-pharmacological treatment of POTS

Q Fu, BD Levine - Autonomic neuroscience, 2018 - Elsevier
Recent research has demonstrated that cardiovascular deconditioning (ie, cardiac atrophy
and hypovolemia) contributes significantly to the Postural Orthostatic Tachycardia Syndrome …

Cardiac autonomic neural remodeling and susceptibility to sudden cardiac death: effect of endurance exercise training

GE Billman - American Journal of Physiology-Heart and …, 2009 - journals.physiology.org
Sudden cardiac death resulting from ventricular tachyarrhythmias remains the leading cause
of death in industrially developed countries, accounting for between 300,000 and 500,000 …

Stress and aging: A neurovisceral integration perspective

JF Thayer, M Mather, J Koenig - Psychophysiology, 2021 - Wiley Online Library
Darwin emphasized the intimate relationship between the brain and the heart over 150
years ago. Healthy aging is associated with significant changes in both the brain and the …

From psychological moments to mortality: A multidisciplinary synthesis on heart rate variability spanning the continuum of time

AH Kemp, J Koenig, JF Thayer - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Heart rate variability (HRV) indexes functioning of the vagus nerve, arguably the most
important nerve in the human body. The Neurovisceral Integration Model has provided a …

A physiological approach to prolonged recovery from sport-related concussion

J Leddy, JG Baker, MN Haider… - Journal of athletic …, 2017 - meridian.allenpress.com
Management of the athlete with postconcussion syndrome (PCS) is challenging because of
the nonspecificity of PCS symptoms. Ongoing symptoms reflect prolonged concussion …