In order to ensure normal body function, the human body is dependent on a tight control of
its blood glucose levels. This is accomplished by a highly sophisticated network of various …

Insulin is a major endocrine hormone also involved in the regulation of energy and lipid
metabolism via the activation of an intracellular signaling cascade involving the insulin …

Accumulation of fat mass in obesity may result from hypertrophy and/or hyperplasia and is
frequently associated with adipose tissue (AT) dysfunction in adults. Here we assessed early …

Adiponectin has received considerable attention for its potential anti-diabetic actions. The
adipokine exerts control of glucose and lipid homeostasis via critical effects within the liver …

This review summarizes recent advances in our understanding of the pre-and
posttranscriptional mechanisms that regulate leptin production and secretion in adipocytes …

Neuronal apoptosis is one of the main pathological processes of hypoxic‐ischemic brain
damage (HIBD) and is involved in the development of hypoxic‐ischemic encephalopathy …

Polygonatum rhizoma polysaccharide (PP) is a main ingredient of Polygonatum rhizoma,
which is both food and traditional herbal medicine. In this study, we aimed to investigate the …

Leptin is a well-known hunger-sensing peptide hormone. The role of leptin in weight gain
and metabolic homeostasis has been explored for the past two decades. In this review, we …

Autophagy dysregulation is implicated in metabolic diseases, including type 2 diabetes.
However, the mechanism by which the autophagy machinery regulates metabolism is …

Aims. Apelin is secreted by adipocytes acting on APJ receptor and plays an important role in
control of feeding behavior, energy expenditure, and the regulation of body fluid …