Physiological assessment of coronary artery disease (CAD) has become one of the
cornerstones of decision making for myocardial revascularization, with a large body of …

Aims The aim of this work was to investigate the prognostic impact of revascularization of
non-culprit lesions in patients with ST-segment elevation myocardial infarction (STEMI) and …

Importance Recently, the Complete vs Culprit-Only Revascularization to Treat Multivessel
Disease After Early PCI (percutaneous coronary intervention) for STEMI (ST-segment …

Owing to recent advances in early reperfusion strategies, pharmacological therapy,
standardized care, and the identification of vulnerable patient subsets, the prognosis of …

Importance Even after fractional flow reserve (FFR)–guided complete revascularization,
patients with myocardial infarction (MI) have high rates of recurrent major adverse …

The clinical value of fractional flow reserve and non-hyperaemic pressure ratios are well
established in determining an indication for percutaneous coronary intervention (PCI) in …

Background Intracoronary physiology is increasingly used in nonculprit stenoses of patients
with acute coronary syndromes (ACS). However, evidence regarding the safety of fractional …

Multivessel disease (MVD) affects approximately 50% of patients with acute coronary
syndromes (ACS) and is significantly burdened by poor outcomes and high mortality. It …

Background Artificial intelligence enables simultaneous evaluation of plaque morphology
and computational physiology from optical coherence tomography (OCT). Objectives This …

Background: The resistive reserve ratio (RRR) expresses the ratio between basal and
hyperemic microvascular resistance. RRR measures the vasodilatory capacity of the …