Integration of GC–MS and LC–MS for untargeted metabolomics profiling

ÖC Zeki, CC Eylem, T Reçber, S Kır… - Journal of Pharmaceutical …, 2020 - Elsevier
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …

High‐throughput metabolomics by 1D NMR

A Vignoli, V Ghini, G Meoni, C Licari… - Angewandte Chemie …, 2019 - Wiley Online Library
Metabolomics deals with the whole ensemble of metabolites (the metabolome). As one of
the‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …

Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics

P Soininen, AJ Kangas, P Würtz, T Suna… - Circulation …, 2015 - Am Heart Assoc
Metabolomics is becoming common in epidemiology due to recent developments in
quantitative profiling technologies and appealing results from their applications for …

An atlas of genetic influences on human blood metabolites

SY Shin, EB Fauman, AK Petersen, J Krumsiek… - Nature …, 2014 - nature.com
Genome-wide association scans with high-throughput metabolic profiling provide
unprecedented insights into how genetic variation influences metabolism and complex …

Metabolomics: the apogee of the omics trilogy

GJ Patti, O Yanes, G Siuzdak - Nature reviews Molecular cell biology, 2012 - nature.com
Metabolites, the chemical entities that are transformed during metabolism, provide a
functional readout of cellular biochemistry. With emerging technologies in mass …

[HTML][HTML] The exposome in practice: design of the EXPOsOMICS project

P Vineis, M Chadeau-Hyam, H Gmuender… - International journal of …, 2017 - Elsevier
Abstract EXPOsOMICS is a European Union funded project that aims to develop a novel
approach to the assessment of exposure to high priority environmental pollutants, by …

Quantitative variability of 342 plasma proteins in a human twin population

Y Liu, A Buil, BC Collins, LCJ Gillet… - Molecular systems …, 2015 - embopress.org
The degree and the origins of quantitative variability of most human plasma proteins are
largely unknown. Because the twin study design provides a natural opportunity to estimate …

Linear mixed-effects modeling approach to FMRI group analysis

G Chen, ZS Saad, JC Britton, DS Pine, RW Cox - Neuroimage, 2013 - Elsevier
Conventional group analysis is usually performed with Student-type t-test, regression, or
standard AN (C) OVA in which the variance–covariance matrix is presumed to have a simple …

From correlation to causation: analysis of metabolomics data using systems biology approaches

A Rosato, L Tenori, M Cascante, PR De Atauri Carulla… - Metabolomics, 2018 - Springer
Introduction Metabolomics is a well-established tool in systems biology, especially in the top–
down approach. Metabolomics experiments often results in discovery studies that provide …

The metabolomics of human aging: Advances, challenges, and opportunities

DJ Panyard, B Yu, MP Snyder - Science Advances, 2022 - science.org
As the global population becomes older, understanding the impact of aging on health and
disease becomes paramount. Recent advancements in multiomic technology have allowed …