Proteins can be modified by post-translational modifications such as phosphorylation,
methylation, acetylation and ubiquitylation, creating binding sites for specific protein …

Tudor domain proteins function as molecular adaptors, binding methylated arginine or lysine
residues on their substrates to promote physical interactions and the assembly of …

Although emerging cell-or animal-based evidence supports the relationship between SND1
and cancers, no pan-cancer analysis is available. We thus first explored the potential …

Regulation of viral RNA biogenesis is fundamental to productive SARS-CoV-2 infection. To
characterize host RNA-binding proteins (RBPs) involved in this process, we biochemically …

Specific sites of histone tail methylation are associated with transcriptional activity at gene
loci. These methyl marks are interpreted by effector molecules, which harbor protein …

Arginine dimethylation plays critical roles in the assembly of ribonucleoprotein complexes in
pre-mRNA splicing and piRNA pathways. We report solution structures of SMN and SPF30 …

PIWI proteins and their bound PIWI‐interacting RNAs (piRNAs) form the core of a gonad‐
specific small RNA silencing pathway that protects the animal genome against the …

Lamin B Receptor (LBR) is an integral membrane protein of the interphase nuclear
envelope (NE). The N-terminal end resides in the nucleoplasm, binding to lamin B and …

Abstract The N6-methyladenosine (m6A) modification plays important regulatory roles in
gene expression, cancer occurrence and metastasis. Herein, we aimed to explore the …

Piwi proteins are modified by symmetric dimethylation of arginine (sDMA), and the
methylarginine-dependent interaction with Tudor domain proteins is critical for their …