Urticaria is an inflammatory skin disorder that affects up to 20% of the world population at
some point during their life. It presents with wheals, angioedema or both due to activation …

Guidelines for the treatment of chronic spontaneous urticaria (CSU) recommend the use of
the IgE-targeted biologic omalizumab in patients with antihistamine-refractory disease. The …

Urticaria has been known as a disease since antiquity. However, in the last decades an
increasing understanding of the mechanisms involved in its pathogenesis has shown the …

Elevated serum IgE levels are associated with allergic disorders, parasitosis and specific
immunologic abnormalities. In addition, epidemiological and mechanistic evidence indicates …

Urticaria and angioedema are very common. Management of chronic urticaria subtypes,
which usually persist for many years, is challenging. Recent years have demonstrated that …

During the last decades, new treatments targeting disease mechanisms referred as
biologics have been introduced in the therapy of asthma and currently, five monoclonal …

In chronic spontaneous urticaria (CSU), wheals, angioedema, or both appear spontaneously
for> 6 weeks. Current recommended treatment options for urticaria target mast cell …

Chronic spontaneous urticaria (CSU) is a debilitating mast cell–driven disease
characterized by recurrent wheals and/or angioedema. Substantial progress has been made …

Background Chronic urticaria (CU) is a common skin disorder, which can be further divided
into chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU) …

Chronic urticaria (CU) and angioedema can occur at any age. Although most CU with or
without angioedema occurs in adults, it can also present in children or the elderly and can …