Contributions of blood–brain barrier imaging to neurovascular unit pathophysiology of Alzheimer's disease and related dementias
The blood–brain barrier (BBB) plays important roles in the maintenance of brain
homeostasis. Its main role includes three kinds of functions:(1) to protect the central nervous …
homeostasis. Its main role includes three kinds of functions:(1) to protect the central nervous …
Light on Alzheimer's disease: from basic insights to preclinical studies
Alzheimer's disease (AD), referring to a gradual deterioration in cognitive function, including
memory loss and impaired thinking skills, has emerged as a substantial worldwide …
memory loss and impaired thinking skills, has emerged as a substantial worldwide …
[HTML][HTML] Evaluation of whole-brain oxygen metabolism in Alzheimer's disease using QSM and quantitative BOLD
Objective The objective of this study was to evaluate the whole-brain pattern of oxygen
extraction fraction (OEF), cerebral blood flow (CBF), and cerebral metabolic rate of oxygen …
extraction fraction (OEF), cerebral blood flow (CBF), and cerebral metabolic rate of oxygen …
Regional White Matter Hyperintensities and Alzheimer's Disease Biomarkers Among Older Adults with Normal Cognition and Mild Cognitive Impairment
P Newton, J Tchounguen, C Pettigrew… - Journal of …, 2023 - content.iospress.com
Background: Alzheimer's disease (AD) frequently co-occurs with other brain pathologies.
Recent studies suggest there may be a mechanistic link between AD and small vessel …
Recent studies suggest there may be a mechanistic link between AD and small vessel …
Cortical oxygen extraction fraction using quantitative BOLD MRI and cerebral blood flow during vasodilation
Introduction: We aimed to demonstrate non-invasive measurements of regional oxygen
extraction fraction (OEF) from quantitative BOLD MRI modeling at baseline and after …
extraction fraction (OEF) from quantitative BOLD MRI modeling at baseline and after …
Brain Frontal-Lobe Misery Perfusion in COVID-19 ICU Survivors: An MRI Pilot Study
Post-acute COVID-19 syndrome (PCS) is highly prevalent. Critically ill patients requiring
intensive care unit (ICU) admission are at a higher risk of developing PCS. The mechanisms …
intensive care unit (ICU) admission are at a higher risk of developing PCS. The mechanisms …
Vessel‐specific quantification of cerebral venous oxygenation with velocity‐encoding preparation and rapid acquisition
Purpose Non‐invasive measurement of cerebral venous oxygenation (Yv) is of critical
importance in brain diseases. The present work proposed a fast method to quantify regional …
importance in brain diseases. The present work proposed a fast method to quantify regional …
Multi-Echo Complex Quantitative Susceptibility Mapping and Quantitative Blood Oxygen Level-Dependent Magnitude (mcQSM+ qBOLD or mcQQ) for Oxygen …
Oxygen extraction fraction (OEF), the fraction of oxygen that tissue extracts from blood, is an
essential biomarker used to directly assess tissue viability and function in neurologic …
essential biomarker used to directly assess tissue viability and function in neurologic …
Metabolic connectivity in ageing.
Information transfer across the brain has a high energetic cost and requires the efficient use
of glucose. Positron emission tomography (PET) studies have shown that ageing is …
of glucose. Positron emission tomography (PET) studies have shown that ageing is …
[PDF][PDF] 脑氧代谢率的功能磁共振成像方法
殷雅彦， 李琼阁， 单艺， 刘霄翊， 卢洁 - 中国医疗设备 - cs.china-cmd.org
目的提出一种可用于脑氧代谢率(Cerebral Metabolic Rate of Oxygen, CMRO2)
功能磁共振成像研究的方法——基于灌注的多回波非对称性自旋回波(Perfusion Multiecho …
功能磁共振成像研究的方法——基于灌注的多回波非对称性自旋回波(Perfusion Multiecho …