Thiazole: A review on chemistry, synthesis and therapeutic importance of its derivatives
M T. Chhabria, S Patel, P Modi… - Current topics in …, 2016 - benthamdirect.com
Thiazole, a unique heterocycle containing sulphur and nitrogen atoms, occupies an
important place in medicinal chemistry. It is an essential core scaffold present in many …
important place in medicinal chemistry. It is an essential core scaffold present in many …
Recent applications of 1, 3-thiazole core structure in the identification of new lead compounds and drug discovery
Thiazole is one of the most important scaffolds in heterocyclic chemistry and drug design
and discovery. It is widely found in diverse pharmacologically active substances and in …
and discovery. It is widely found in diverse pharmacologically active substances and in …
Visible light photocatalysis in the synthesis of pharmaceutically relevant heterocyclic scaffolds
Visible light and photoredox catalysis have emerged as a powerful and long-lasting tool for
organic synthesis, demonstrating the importance of a variety of chemical bond formation …
organic synthesis, demonstrating the importance of a variety of chemical bond formation …
Coumarin: a potential nucleus for anti-inflammatory molecules
Numerous research reports have indicated the coumarin nucleus as a potential candidate
for development of anti-inflammatory drugs. Various phytoconstituents such as …
for development of anti-inflammatory drugs. Various phytoconstituents such as …
Recent developments of 2-aminothiazoles in medicinal chemistry
Abstract The 2-aminothiazole (2-AT) core is an active pharmacophore and used in medicinal
chemistry and drug discovery research. A number of drugs with 2-AT core are in the market …
chemistry and drug discovery research. A number of drugs with 2-AT core are in the market …
Thiazoles and thiazolidinones as COX/LOX inhibitors
K Liaras, M Fesatidou, A Geronikaki - Molecules, 2018 - mdpi.com
Inflammation is a natural process that is connected to various conditions and disorders such
as arthritis, psoriasis, cancer, infections, asthma, etc. Based on the fact that cyclooxygenase …
as arthritis, psoriasis, cancer, infections, asthma, etc. Based on the fact that cyclooxygenase …
Thiazoles: having diverse biological activities
In the last few decades, a lot of work has been done on thiazole ring to find new compounds
related to this scaffold to act as antioxidant, analgesic, anti-inflammatory, antimicrobial …
related to this scaffold to act as antioxidant, analgesic, anti-inflammatory, antimicrobial …
Coumarins as privileged scaffold for anti-inflammatory drug development
J Grover, SM Jachak - Rsc Advances, 2015 - pubs.rsc.org
Several literature reports had highlighted the significance of coumarin nucleus as a source
of potential candidates for anti-inflammatory drug development. Various natural coumarins …
of potential candidates for anti-inflammatory drug development. Various natural coumarins …
Synthesis, crystal structure, Hirshfeld surface investigation and comparative DFT studies of ethyl 2-[2-(2-nitrobenzylidene) hydrazinyl] thiazole-4-carboxylate
Abstract The ethyl 2-[2-(2-nitrobenzylidene) hydrazinyl] thiazole-4-carboxylate (1), a thiazole
ester, was synthesized by refluxing 1-(2-nitrobenzylidene) thiosemicarbazide and ethyl …
ester, was synthesized by refluxing 1-(2-nitrobenzylidene) thiosemicarbazide and ethyl …
[PDF][PDF] Thiazoles: a valuable insight into the recent advances and biological activities
Thiazoles displayed broad range of biological activities and found in many potent
biologically active molecules such as Sulfathiazol (antimicrobial drug), Ritonavir …
biologically active molecules such as Sulfathiazol (antimicrobial drug), Ritonavir …