Classical Hodgkin lymphoma (cHL) is unique among lymphoid malignancies in several key
biological features.(i) The Hodgkin and Reed-Sternberg (HRS) tumor cells are rare among …

Epstein–Barr virus (EBV), originally discovered through its association with Burkitt
lymphoma, is now aetiologically linked to a remarkably wide range of lymphoproliferative …

Epstein–Barr virus (EBV) was discovered 40 years ago from examining electron
micrographs of cells cultured from Burkitt's lymphoma, a childhood tumour that is common in …

Chromosomal translocations involving the immunoglobulin loci are a hallmark of many types
of B-cell lymphoma. Other factors, however, also have important roles in the pathogenesis of …

Hodgkin's lymphoma was first described in 1832. The aetiology of this lymphoma, however,
remained enigmatic for a long time. Only within the past 10 years has the B-cell nature of the …

Hodgkin lymphoma (HL), a B cell–derived cancer, is one of the most common lymphomas. In
HL, the tumor cells—Hodgkin and Reed-Sternberg (HRS) cells—are usually very rare in the …

Mediastinal large B-cell lymphoma (MLBCL) is a recently identified subtype of diffuse large
B-cell lymphoma (DLBCL) that characteristically presents as localized tumors in young …

Epstein–Barr virus (EBV) is an extremely successful virus, infecting more than 90% of the
human population worldwide. After primary infection, the virus persists for the life of the host …

Hodgkin lymphoma (HL) is a B cell lymphoma characterized by few malignant cells and
numerous immune effector cells in the tumour microenvironment. The incidence of HL is …

The pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma (NLPHL) and its
relationship to other lymphomas are largely unknown. This is partly because of the technical …