The gut microbiota and respiratory diseases: new evidence
L Chunxi, L Haiyue, L Yanxia… - Journal of immunology …, 2020 - Wiley Online Library
Human body surfaces, such as the skin, intestines, and respiratory and urogenital tracts, are
colonized by a large number of microorganisms, including bacteria, fungi, and viruses, with …
colonized by a large number of microorganisms, including bacteria, fungi, and viruses, with …
Pathogens, microbiome and the host: emergence of the ecological Koch's postulates
P Vonaesch, M Anderson… - FEMS microbiology …, 2018 - academic.oup.com
Even though tremendous progress has been made in the last decades to elucidate the
mechanisms of intestinal homeostasis, dysbiosis and disease, we are only at the beginning …
mechanisms of intestinal homeostasis, dysbiosis and disease, we are only at the beginning …
PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques
KD Kauffman, S Sakai, NE Lora, S Namasivayam… - Science …, 2021 - science.org
Boosting immune cell function by targeting the coinhibitory receptor PD-1 may have
applications in the treatment of chronic infections. Here, we examine the role of PD-1 during …
applications in the treatment of chronic infections. Here, we examine the role of PD-1 during …
Antibiotic treatment for Tuberculosis induces a profound dysbiosis of the microbiome that persists long after therapy is completed
MF Wipperman, DW Fitzgerald, MAJ Juste, Y Taur… - Scientific reports, 2017 - nature.com
Mycobacterium tuberculosis, the cause of Tuberculosis (TB), infects one third of the world's
population and causes substantial mortality worldwide. In its shortest format, treatment of TB …
population and causes substantial mortality worldwide. In its shortest format, treatment of TB …
An interleukin-23-interleukin-22 axis regulates intestinal microbial homeostasis to protect from diet-induced atherosclerosis
Although commensal flora is involved in the regulation of immunity, the interplay between
cytokine signaling and microbiota in atherosclerosis remains unknown. We found that …
cytokine signaling and microbiota in atherosclerosis remains unknown. We found that …
The gut microbiome signatures discriminate healthy from pulmonary tuberculosis patients
Cross talk occurs between the human gut and the lung through a gut-lung axis involving the
gut microbiota. However, the signatures of the human gut microbiota after active …
gut microbiota. However, the signatures of the human gut microbiota after active …
Gut microbiota associated with pulmonary tuberculosis and dysbiosis caused by anti-tuberculosis drugs
Y Hu, Q Yang, B Liu, J Dong, L Sun, Y Zhu, H Su… - Journal of Infection, 2019 - Elsevier
Background: An improved understanding of the gut microbiota could lead to better strategies
for the diagnosis, therapy and prophylaxis of tuberculosis (TB). The impact of both …
for the diagnosis, therapy and prophylaxis of tuberculosis (TB). The impact of both …
Intestinal dysbiosis compromises alveolar macrophage immunity to Mycobacterium tuberculosis
N Khan, L Mendonca, A Dhariwal, G Fontes… - Mucosal …, 2019 - nature.com
Current treatments for tuberculosis (TB) are effective in controlling Mycobacterium
tuberculosis (Mtb) growth, yet have significant side effects and do not prevent reinfection …
tuberculosis (Mtb) growth, yet have significant side effects and do not prevent reinfection …
The microbiome and tuberculosis: state of the art, potential applications, and defining the clinical research agenda
The diverse microbial communities within our bodies produce metabolites that modulate
host immune responses. Even the microbiome at distal sites has an important function in …
host immune responses. Even the microbiome at distal sites has an important function in …
The value of transcriptomics in advancing knowledge of the immune response and diagnosis in tuberculosis
Blood transcriptomics analysis of tuberculosis has revealed an interferon-inducible gene
signature that diminishes in expression after successful treatment; this promises improved …
signature that diminishes in expression after successful treatment; this promises improved …