Inflammation and preterm birth

M Cappelletti, S Della Bella, E Ferrazzi… - Journal of Leucocyte …, 2016 - academic.oup.com
Preterm birth is the leading cause of neonatal morbidity and mortality. Although the
underlying causes of pregnancy-associated complication are numerous, it is well …

Intrauterine infection and preterm labor

V Agrawal, E Hirsch - Seminars in Fetal and Neonatal Medicine, 2012 - Elsevier
Preterm labor is defined as labor that begins before 37 completed weeks of pregnancy.
More than 12% of infants born in the USA are preterm. At least 40% of preterm births are …

The Th1: th2 dichotomy of pregnancy and preterm labour

L Sykes, DA MacIntyre, XJ Yap, TG Teoh… - Mediators of …, 2012 - Wiley Online Library
Pregnancy is a unique immunological state in which a balance of immune tolerance and
suppression is needed to protect the fetus without compromising the mother. It has long …

The determinant role of IL-6 in the establishment of inflammation leading to spontaneous preterm birth

E Prairie, F Cote, M Tsakpinoglou, M Mina… - Cytokine & growth factor …, 2021 - Elsevier
Preterm birth (PTB) and its consequences are a major public health concern as preterm
delivery is the main cause of mortality and morbidity at birth. There are many causes of PTB …

Interplay of cytokines in preterm birth

M Pandey, M Chauhan, S Awasthi - Indian Journal of Medical …, 2017 - journals.lww.com
Preterm infants (ie., born before< 37 wk of gestation) are at increased risk of morbidity and
mortality and long-term disabilities. Global prevalence of preterm birth (PTB) varies from 5 to …

Neuroinflammation in preterm babies and autism spectrum disorders

C Bokobza, J Van Steenwinckel, S Mani, V Mezger… - Pediatric …, 2019 - nature.com
Genetic anomalies have a role in autism spectrum disorders (ASD). Each genetic factor is
responsible for a small fraction of cases. Environment factors, like preterm delivery, have an …

Role of maternal periodontitis in preterm birth

H Ren, M Du - Frontiers in immunology, 2017 - frontiersin.org
In the last two decades, many studies have focused on whether periodontitis is a risk factor
for preterm birth (PTB). However, both epidemiological investigation and intervention trials …

Genetic polymorphisms and recurrent spontaneous abortions: an overview of current knowledge

S Daher, R Mattar… - American Journal of …, 2012 - Wiley Online Library
The relevance of gene polymorphisms in the development of unexplained recurrent
spontaneous abortion is still unclear. Cytokines, angiogenic mediators, and hormones are …

Spontaneous preterm birth and single nucleotide gene polymorphisms: a recent update

IA Sheikh, E Ahmad, MS Jamal, M Rehan, M Assidi… - BMC genomics, 2016 - Springer
Background Preterm birth (PTB), birth at< 37 weeks of gestation, is a significant global public
health problem. World-wide, about 15 million babies are born preterm each year resulting in …

Inflammatory factors, genetic variants, and predisposition for preterm birth

J Couceiro, I Matos, JJ Mendes, PV Baptista… - Clinical …, 2021 - Wiley Online Library
Preterm birth is a major clinical and public health challenge, with a prevalence of 11%
worldwide. It is the leading cause of death in children younger than 5 years old and …