Mycobacterium tuberculosis is a leading cause of mortality worldwide and establishes a
long-lived latent infection in a substantial proportion of the human population. Multiple lines …

Inhibitors of histone deacetylases (HDACs) are nowadays part of the therapeutic arsenal
mainly against cancers, with four compounds approved by the Food and Drug …

Entomopathogenic fungus as well as their toxins is a natural threat surrounding social insect
colonies. To defend against them, social insects have evolved a series of unique disease …

Mycobacterium tuberculosis (Mtb) infection reveals complex and dynamic host-pathogen
interactions, leading to host protection or pathogenesis. Using a unique transcriptome …

Tuberculosis is a stern, difficult to treat chronic infection caused by acid-fast bacilli that tend
to take a long time to be eradicated from the host's environment. It requires the action of both …

Mycobacterium tuberculosis (M. tuberculosis) has coevolved with humans for millennia and
developed multiple mechanisms to evade host immunity. Restoring host immunity in order to …

In medicines development, the progress in science and technology is accelerating.
Awareness of these developments and their associated challenges and opportunities is …

Mycobacterium tuberculosis has evolved several mechanisms to counter host defense
arsenals for its proliferation. Here we report that M. tuberculosis employs a multi-pronged …

The rapid and persistent increase of drug-resistant Mycobacterium tuberculosis (Mtb)
infections poses increasing global problems in combatting tuberculosis (TB), prompting for …

Bacteria evolved many strategies to survive and persist within host cells. Secretion of
bacterial effectors enables bacteria not only to enter the host cell but also to manipulate host …