Alzheimer's disease (AD) is the most common cause of dementia associated with a
progressive neurodegenerative disorder, with a prevalence of 44 million people throughout …

Obesity is increasing at unprecedented levels globally, and the overall impact of obesity on
the various organ systems of the body is only beginning to be fully appreciated. Because of …

Many mammals have evolved to be social creatures. In humans, the ability to learn from
others' experiences is essential to survival; and from an early age, individuals are …

The perinatal period is a window of heightened plasticity that lays the groundwork for future
anatomic, physiologic, and behavioral outcomes. During this time, maternal diet plays a …

There is accumulating evidence from epidemiological studies that changes in body weight
are associated with Alzheimer's disease (AD) from mid-life obesity increasing the risk of …

Psychiatric disorders are caused by complex and diverse factors, and numerous
mechanisms have been proposed for the pathogenesis of these disorders. Accumulating …

Brain-derived neurotrophic factor (BDNF) signals through its high affinity receptor
Tropomyosin receptor kinase-B (TrkB) to regulate neuronal development, synapse formation …

This article is part of a Special Issue “SBN 2014”. Obesity in women of child-bearing age is a
growing problem in developed and developing countries. Evidence from human studies …

Transient receptor potential (TRP) family proteins form tetrameric nonselective cation
channels. Upon activation, TRP channels depolarize the membrane potential, which can …

Leptin regulates both feeding and glycaemia primarily through its receptors expressed on
agouti-related peptide (AgRP) and pro-opiomelanocortin-expressing (POMC) neurons; …