Carbonyl–olefin metathesis

H Albright, AJ Davis, JL Gomez-Lopez… - Chemical …, 2021 - ACS Publications
This Review describes the development of strategies for carbonyl–olefin metathesis
reactions relying on stepwise, stoichiometric, or catalytic approaches. A comprehensive …

Recent advances in the biosynthesis strategies of nitrogen heterocyclic natural products

B Gao, B Yang, X Feng, C Li - Natural Product Reports, 2022 - pubs.rsc.org
Covering: 2015 to 2020 Nitrogen heterocyclic natural products (NHNPs) are primary or
secondary metabolites containing nitrogen heterocyclic (N-heterocyclic) skeletons. Due to …

Iron(III)-catalysed carbonyl–olefin metathesis

JR Ludwig, PM Zimmerman, JB Gianino, CS Schindler - Nature, 2016 - nature.com
The olefin metathesis reaction of two unsaturated substrates is one of the most powerful
carbon–carbon-bond-forming reactions in organic chemistry. Specifically, the catalytic olefin …

Scaffold diversity synthesis and its application in probe and drug discovery

M Garcia‐Castro, S Zimmermann… - Angewandte Chemie …, 2016 - Wiley Online Library
Scaffold diversity is a crucial feature of compound collections that has a huge impact on their
success in biological screenings. The synthesis of highly complex and diverse scaffolds …

Beyond olefins: new metathesis directions for synthesis

MR Becker, RB Watson, CS Schindler - Chemical Society Reviews, 2018 - pubs.rsc.org
The olefin–olefin metathesis reaction has emerged as one of the most important carbon–
carbon bond-forming reactions, as illustrated by its wide use in the synthesis of complex …

Brønsted Acid‐Catalyzed Carbonyl‐Olefin Metathesis inside a Self‐Assembled Supramolecular Host

L Catti, K Tiefenbacher - Angewandte Chemie International …, 2018 - Wiley Online Library
Carbonyl–olefin metathesis represents a powerful yet underdeveloped method for the
formation of carbon–carbon bonds. So far, no Brønsted acid based method for the catalytic …

Mechanistic investigations of the iron (III)-catalyzed carbonyl-olefin metathesis reaction

JR Ludwig, S Phan, CC McAtee… - Journal of the …, 2017 - ACS Publications
Iron (III)-catalyzed carbonyl-olefin ring-closing metathesis represents a new approach
toward the assembly of molecules traditionally generated by olefin–olefin metathesis or …

Tropylium-promoted carbonyl–olefin metathesis reactions

UPN Tran, G Oss, DP Pace, J Ho, TV Nguyen - Chemical science, 2018 - pubs.rsc.org
The carbonyl–olefin metathesis (COM) reaction is a highly valuable chemical transformation
in a broad range of applications. However, its scope is much less explored compared to …

Carbonyl–olefin metathesis catalyzed by molecular iodine

UPN Tran, G Oss, M Breugst, E Detmar, DP Pace… - ACS …, 2018 - ACS Publications
The carbonyl–olefin metathesis reaction could facilitate rapid functional group
interconversion and allow construction of complicated organic structures. Herein, we …

Iron-catalyzed ortho C–H homoallylation of aromatic ketones with methylenecyclopropanes

N Kimura, S Katta, Y Kitazawa, T Kochi… - Journal of the …, 2021 - ACS Publications
We report here a C–H homoallylation reaction of aromatic ketones with
methylenecyclopropanes (MCPs) only using a catalytic amount of Fe (PMe3) 4. A variety of …