Background It has been reported that diabetes mellitus affects 435 million people globally as
a primary health care problem. Despite many therapies available, many diabetes remains …

Diabetes mellitus (DM) is a fast-growing chronic metabolic disorder that leads to significant
health, social, and economic problems worldwide. Chronic hyperglycemia caused by DM …

Aberrant alternative splicing (AS) of pre-mRNAs promotes the development and proliferation
of cancerous cells. Accordingly, we had previously observed higher levels of the aryl …

Cataract is a global eye disease caused by the opacification of lens, while its underlying
molecular pathogenesis is not clear, making it difficult for prevention. CELF1, an RNA …

RBFOX2, which has a well-established role in alternative splicing, is linked to heart
diseases. However, it is unclear whether RBFOX2 has other roles in RNA processing that …

Circular RNAs (circRNAs) are crucial regulators of β-cell function and are involved in
lipotoxicity-induced β-cell damage in type 2 diabetes mellitus (T2DM). We previously …

Alternative splicing (AS) is dysregulated in Type 1 diabetic (T1D) hearts but mechanisms
responsible are unclear. Here, we provide evidence that the RNA binding protein (RBP) …

RNA-binding proteins (RBPs) play important roles in regulating the expression of genes
involved in human physiological and pathological processes, especially in cancers. Many …

Background RNA binding proteins (RBPs)-mediated regulation plays important roles in
many eye diseases, including the canonical RBP CELF1 in cataract. While the definite …

RNA-binding proteins (RBPs) are integral components of cellular machinery, playing crucial
roles in the regulation of gene expression and maintaining genetic stability. Their …