Neutrophils are the most abundant white blood cells in circulation, and patients with
congenital neutrophil deficiencies suffer from severe infections that are often fatal …

The fundamental role played by neutrophils for an efficient, acute inflammatory response
has long been appreciated, with the underlying molecular and cellular mechanisms largely …

Neutrophils are known to play an important role in inflammatory responses by virtue of their
ability to perform a series of effector functions that collectively represent a major mechanism …

The intracellular protozoan Toxoplasma gondii is a widespread opportunistic parasite of
humans and animals. Normally, T. gondii establishes itself within brain and skeletal muscle …

It has been documented that strenuous exercise not only induces pyrogenesis but also
elicits mobilization and functional augmentation of neutrophils and monocytes whereas it …

Cytokines orchestrate the complex netuwrk of cellular interactions that regulate effector cell
functions of natural and immune resistance. Although T cells, natural killer (NK) cells and …

Publisher Summary This chapter summarizes the recent knowledge on the production of
cytokines by neutrophils in vitro and in vivo—particularly molecular regulation and other …

The early induction of interleukin (IL)-12 is a critical event in determining the development of
both innate resistance and adaptive immunity to many intracellular pathogens. Previous in …

Neutrophils (PMN) have been described as critical effector cells in the host's antibacterial
innate immunities. However, the classification of murine PMNs remains unclear. Here, we …

Neutrophils play a major role in the innate immune system and are normally considered to
be short-lived effector cells that exert anti-microbial activity and sometimes …