Boron chemicals in diagnosis and therapeutics
Advances in the field of boron chemistry have expanded the application of boron from
material use to medicine. Boron-based drugs represent a new class of molecules that …
material use to medicine. Boron-based drugs represent a new class of molecules that …
Hexagonal boron nitrides (white graphene): a promising method for cancer drug delivery
SM Sharker - International Journal of Nanomedicine, 2019 - Taylor & Francis
Advances in low-dimensions nanomaterials drug-carrier have rapidly translated into clinical
practice. Interestingly, the two-dimensional (2D) nanomaterials of hexagonal boron nitride (h …
practice. Interestingly, the two-dimensional (2D) nanomaterials of hexagonal boron nitride (h …
Synthesis and applications of perfunctionalized boron clusters
JC Axtell, LMA Saleh, EA Qian, AI Wixtrom… - Inorganic …, 2018 - ACS Publications
This Viewpoint describes major advances pertaining to perfunctionalized boron clusters in
synthesis and their respective applications. The first portion of this work highlights key …
synthesis and their respective applications. The first portion of this work highlights key …
Synthesis of biologically active boron-containing compounds
F Yang, M Zhu, J Zhang, H Zhou - MedChemComm, 2018 - pubs.rsc.org
Boron-containing compounds which possess unique and attractive properties have received
increasing attention from the pharmaceutical industry and academia recently. They have …
increasing attention from the pharmaceutical industry and academia recently. They have …
Boron‐based drug design
HS Ban, H Nakamura - The Chemical Record, 2015 - Wiley Online Library
The use of the element boron, which is not generally observed in a living body, possesses a
high potential for the discovery of new biological activity in pharmaceutical drug design. In …
high potential for the discovery of new biological activity in pharmaceutical drug design. In …
Benzoxaborole compounds for therapeutic uses: a patent review (2010-2018)
Introduction: Benzoxaborole is a versatile boron-heterocyclic scaffold which has found in the
last 10 years a broad spectrum of applications in medicinal chemistry, due to its …
last 10 years a broad spectrum of applications in medicinal chemistry, due to its …
Boron-containing compounds: chemico-biological properties and expanding medicinal potential in prevention, diagnosis and therapy
MA Soriano-Ursúa, BC Das… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Although the medicinal use of boron-containing compounds (BCCs) had long
been limited to antiseptics, in the last few decades, these compounds have been used as …
been limited to antiseptics, in the last few decades, these compounds have been used as …
Current data regarding the structure-toxicity relationship of boron-containing compounds
ED Farfán-García, NT Castillo-Mendieta… - Toxicology letters, 2016 - Elsevier
Boron is ubiquitous in nature, being an essential element of diverse cells. As a result,
humans have had contact with boron containing compounds (BCCs) for a long time. During …
humans have had contact with boron containing compounds (BCCs) for a long time. During …
Organoboronic acids/esters as effective drug and prodrug candidates in cancer treatments: challenge and hope
MK Al-Omari, M Elaarag, RM Al-Zoubi… - Journal of Enzyme …, 2023 - Taylor & Francis
Boronic acids/esters have recently emerged in the field of medicinal and pharmaceutical
research due to their exceptional oxophilicity, low toxicity, and unique structure. They are …
research due to their exceptional oxophilicity, low toxicity, and unique structure. They are …
Synthesis of naphthalimide-carborane and metallacarborane conjugates: Anticancer activity, DNA binding ability
J Nekvinda, D Różycka, S Rykowski, E Wyszko… - Bioorganic …, 2020 - Elsevier
Abstract The development of 1, 8-naphthalimide derivatives as DNA-targeting anticancer
agents is a rapidly growing area and has resulted in several derivatives entering into clinical …
agents is a rapidly growing area and has resulted in several derivatives entering into clinical …