Metabolic signatures provide novel insights to Picrorhiza kurroa adaptation along the altitude in Himalayan region

M Kumari, R Joshi, R Kumar - Metabolomics, 2020 - Springer
Introduction Along the altitude, environmental conditions vary significantly that might
influence plant performance and distribution. Adaptation to these changing conditions is a …

Elevated CO2 and temperature influence key proteins and metabolites associated with photosynthesis, antioxidant and carbon metabolism in Picrorhiza kurroa

R Kumar, R Joshi, M Kumari, R Thakur, D Kumar… - Journal of …, 2020 - Elsevier
Global warming is currently one of the most serious issues in ecology. Rising CO 2 level and
temperature have begun to impact life cycles, distribution and yield of various plants yet …

Endomicrobiome of in vitro and natural plants deciphering the endophytes-associated secondary metabolite biosynthesis in Picrorhiza kurrooa, a Himalayan …

A Tamang, M Swarnkar, P Kumar, D Kumar… - Microbiology …, 2023 - Am Soc Microbiol
Picrorhiza kurrooa an endangered high-altitude Himalayan medicinal herb, is used as a
potent hepatoprotective due to the presence of various secondary metabolites, with …

Complexity of gene paralogues resolved in biosynthetic pathway of hepatoprotective iridoid glycosides in a medicinal herb, Picrorhiza kurroa through differential NGS …

A Kharb, RS Chauhan - Molecular Genetics and Genomics, 2021 - Springer
Picrorhiza kurroa is a medicinal herb with diverse pharmacological applications due to the
presence of iridoid glycosides, picroside-I (PI), and picroside-II (P-II), among others. Any …

Bioprocess development for enhancing cell biomass, differential picrosides accumulation, and gene expression profiling at shake flask levels in suspension cultures of …

M Partap, S Rattan, D Kumar, AR Warghat - Industrial Crops and Products, 2022 - Elsevier
Plant cell suspension culture is an alternative and perpetual source for large-scale
metabolites production in significantly less time. However, this approach has not yet been …

Growth dynamics and differential accumulation of picrosides and its precursor metabolites in callus cell lines of Picrorhiza kurroa with distinct anti-steatotic potential

M Partap, J Chhimwal, P Kumar, D Kumar… - Process …, 2022 - Elsevier
Picrorhiza kurroa is an industrially important Himalayan medicinal herb and is well known
for its therapeutic potent picrosides compounds. The limited availability and medicinal usage …

In-depth assembly of organ and development dissected Picrorhiza kurroa proteome map using mass spectrometry

M Kumari, UK Pradhan, R Joshi, A Punia, R Shankar… - BMC Plant …, 2021 - Springer
Abstract Background Picrorhiza kurroa Royle ex Benth. being a rich source of
phytochemicals, is a promising high altitude medicinal herb of Himalaya. The medicinal …

[HTML][HTML] Transcriptome profiling reveal key hub genes in co-expression networks involved in Iridoid glycosides biosynthetic machinery in Picrorhiza kurroa

A Sharma, D Bhattacharyya, S Sharma, RS Chauhan - Genomics, 2021 - Elsevier
Picrorhiza kurroa is a medicinal herb rich in hepatoprotective iridoid glycosides, picroside-I
(PI) and picroside-II (P-II). The biosynthetic machinery of picrosides is poorly understood …

Elicitors Mediated Enhancement of Picrosides and Their Pathway Precursors in Dedifferentiated Cell Suspension Culture of Picrorhiza kurroa Royle ex Benth

M Partap, A Kumar, P Kumar, D Kumar… - Journal of Plant Growth …, 2024 - Springer
Elicitors trigger complex signaling cascades within plants, enhancing secondary metabolite
production. The present study investigated the impact of various elicitors on the …

Pathway Gene Paralogues and Transcription Factors Differentially Associate with Contents of Picrosides in Tissues and Populations of a Medicinal Herb, Picrorhiza …

R Pandey, A Kharb, A Sharma, H Sood… - Biochemical …, 2024 - Springer
Picrorhiza kurroa is a valuable medicinal herb of Himalayan region, containing two major
pharmacological iridoid glycosides: Picroside-I and Picroside-II, in addition to several other …