Frontotemporal lobar degeneration

M Grossman, WW Seeley, AL Boxer, AE Hillis… - Nature Reviews …, 2023 - nature.com
Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset
dementia and presents with early social–emotional–behavioural and/or language changes …

Neurofilament proteins as biomarkers to monitor neurological diseases and the efficacy of therapies

A Yuan, RA Nixon - Frontiers in neuroscience, 2021 - frontiersin.org
Biomarkers of neurodegeneration and neuronal injury have the potential to improve
diagnostic accuracy, disease monitoring, prognosis, and measure treatment efficacy …

Clinical neurology and epidemiology of the major neurodegenerative diseases

MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …

Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders

S Ducharme, A Dols, R Laforce, E Devenney, F Kumfor… - Brain, 2020 - academic.oup.com
The behavioural variant of frontotemporal dementia (bvFTD) is a frequent cause of early-
onset dementia. The diagnosis of bvFTD remains challenging because of the limited …

Frontotemporal dementia

J Bang, S Spina, BL Miller - The Lancet, 2015 - thelancet.com
Frontotemporal dementia is an umbrella clinical term that encompasses a group of
neurodegenerative diseases characterised by progressive deficits in behaviour, executive …

Frontotemporal dementia

NT Olney, S Spina, BL Miller - Neurologic clinics, 2017 - neurologic.theclinics.com
Frontotemporal dementia (FTD) has undergone numerous changes in nomenclature and
categorization schemes since it was first described by Pick in 1892. Presently, FTD …

The Mild Behavioral Impairment Checklist (MBI-C): a rating scale for neuropsychiatric symptoms in pre-dementia populations

Z Ismail, L Agüera-Ortiz, H Brodaty… - Journal of …, 2017 - journals.sagepub.com
Background: Mild behavioral impairment (MBI) is a construct that describes the emergence
at≥ 50 years of age of sustained and impactful neuropsychiatric symptoms (NPS), as a …

Neuropsychiatric symptoms as early manifestations of emergent dementia: provisional diagnostic criteria for mild behavioral impairment

Z Ismail, EE Smith, Y Geda, D Sultzer, H Brodaty… - Alzheimer's & …, 2016 - Elsevier
Neuropsychiatric symptoms (NPS) are common in dementia and in predementia syndromes
such as mild cognitive impairment (MCI). NPS in MCI confer a greater risk for conversion to …

Excitotoxicity: bridge to various triggers in neurodegenerative disorders

A Mehta, M Prabhakar, P Kumar, R Deshmukh… - European journal of …, 2013 - Elsevier
Glutamate is one of the most prominent neurotransmitter in the body, present in over 50% of
nervous tissue and plays an important role in neuronal excitation. This neuronal excitation is …

Alzheimer's disease: clinical update on epidemiology, pathophysiology and diagnosis

D Eratne, SM Loi, S Farrand, W Kelso… - Australasian …, 2018 - journals.sagepub.com
Objectives: To provide a clinical update for general psychiatrists on the assessment and
diagnosis of Alzheimer's disease (AD), highlighting current issues regarding epidemiology …