Host specificity of bacterial pathogens

A Bäumler, FC Fang - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Most pathogens are able to infect multiple hosts but some are highly adapted to a single-
host species. A detailed understanding of the basis of host specificity can provide important …

The streptomycin mouse model for Salmonella diarrhea: functional analysis of the microbiota, the pathogen's virulence factors, and the host's mucosal immune …

P Kaiser, M Diard, B Stecher… - Immunological reviews, 2012 - Wiley Online Library
The mammalian intestine is colonized by a dense microbial community, the microbiota.
Homeostatic and symbiotic interactions facilitate the peaceful co‐existence between the …

Like will to like: abundances of closely related species can predict susceptibility to intestinal colonization by pathogenic and commensal bacteria

B Stecher, S Chaffron, R Käppeli, S Hapfelmeier… - PLoS …, 2010 - journals.plos.org
The intestinal ecosystem is formed by a complex, yet highly characteristic microbial
community. The parameters defining whether this community permits invasion of a new …

The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea

K Endt, B Stecher, S Chaffron, E Slack… - PLoS …, 2010 - journals.plos.org
Many enteropathogenic bacteria target the mammalian gut. The mechanisms protecting the
host from infection are poorly understood. We have studied the protective functions of …

Virulence Gene Profiling and Pathogenicity Characterization of Non-Typhoidal Salmonella Accounted for Invasive Disease in Humans

J Suez, S Porwollik, A Dagan, A Marzel, YI Schorr… - PloS one, 2013 - journals.plos.org
Human infection with non-typhoidal Salmonella serovars (NTS) infrequently causes invasive
systemic disease and bacteremia. To understand better the nature of invasive NTS (iNTS) …

Salmonella pathogenesis and host-adaptation in farmed animals

MP Stevens, RA Kingsley - Current opinion in microbiology, 2021 - Elsevier
Highlights•Genomic signatures of host-adaptation and virulence of Salmonella are
emerging.•Sequence analyses can aid the prediction of zoonotic risk and source …

Motility allows S. Typhimurium to benefit from the mucosal defence

B Stecher, M Barthel, MC Schlumberger… - Cellular …, 2008 - Wiley Online Library
The mammalian intestine is colonized by a dense bacterial community, called microbiota.
The microbiota shields from intestinal infection (colonization resistance). Recently, we have …

Pathogenesis of enteric Salmonella infections

GA Grassl, BB Finlay - Current opinion in gastroenterology, 2008 - journals.lww.com
Pathogenesis of enteric Salmonella infections : Current Opinion in Gastroenterology
Pathogenesis of enteric Salmonella infections : Current Opinion in Gastroenterology Log in or …

Characterization of a Novel Diarrheagenic Strain of Proteus mirabilis Associated With Food Poisoning in China

Z Gong, X Shi, F Bai, X He, H Zhang, Y Li… - Frontiers in …, 2019 - frontiersin.org
Proteus mirabilis is commonly considered to be an opportunistic pathogen causing urinary
tract infections (UTIs) in humans. However, some strains of P. mirabilis were found to be …

Infection of mice by Salmonella enterica serovar Enteritidis involves additional genes that are absent in the genome of serovar Typhimurium

CA Silva, CJ Blondel, CP Quezada… - Infection and …, 2012 - Am Soc Microbiol
Salmonella enterica serovar Enteritidis causes a systemic, typhoid-like infection in newly
hatched poultry and mice. In the present study, a library of 54,000 transposon mutants of S …