Lentiviral vectors (LV) have seen considerably increase in use as gene therapy vectors for
the treatment of acquired and inherited diseases. This review presents the state of the art of …

Introduction: Lentiviruses are a very potent class of viral vectors for which there is presently a
rapidly growing interest for a number of gene therapy. However, their construction …

Background Lentiviral vectors (LV) offer several advantages over other gene delivery
vectors. Their potential for the integration and long‐term expression of therapeutic genes …

Chikungunya virus (CHIKV) is a re-emerging, mosquito-transmitted, enveloped positive
stranded RNA virus. Chikungunya fever is characterized by acute and chronic debilitating …

Lentiviral vectors (LVs) are excellent tools to promote gene transfer and stable gene
expression. Their potential has been already demonstrated in gene therapy clinical trials for …

Lentiviral vectors (LVVs) play a critical role in gene delivery for ex vivo gene-modified cell
therapies. However, the lack of scalable LVV production methods and the high cost …

Lentiviral vectors (LV) are promising tools for gene and cell therapy. They are presently used
in several clinical trials as in vivo or ex vivo gene delivery vectors. However their mass …

Lentiviral vectors are an ideal choice for delivering gene-editing components to cells due to
their capacity for stably transducing a broad range of cells and mediating high levels of gene …

Viral vectors are among the main approaches currently used in studies for executing gene
delivery to target cells. During the past decades of active studies in gene therapy, including …

Transfection of surface adherent cells remain as a standard methodology for lentiviral
production for early phase clinical studies and research purposes. Production today is …