A distinctive tract of all the forms of Alzheimer's disease is the extracellular deposition of a 40–
42/43 amino acid-long peptide derived from the so-called β-amyloid precursor protein …

Oncogenic KRAS (KRAS*) contributes to many cancer hallmarks. In colorectal cancer,
KRAS* suppresses antitumor immunity to promote tumor invasion and metastasis. Here, we …

Enigmatic mechanisms restore the resting state in activated lymphocytes following human
immunodeficiency virus type 1 (HIV-1) infection, rarely allowing persistent nonproductive …

Abstract Grainyhead-like 2 (GRHL2), one of the three homologs of Drosophila grainyhead,
contributes to epithelial morphogenesis and differentiation. Dysregulation of GRHL2 has …

Repression of human immunodeficiency virus type 1 (HIV-1) transcription may contribute to
the establishment or maintenance of proviral quiescence in infected CD4+ cells. The host …

Motivation: Computational prediction and analysis of transcription regulatory regions in DNA
sequences has the potential to accelerate greatly our understanding of how cellular …

Defects in closure of embryonic tissues such as the neural tube, body wall, face and eye
lead to severe birth defects. Cell adhesion is hypothesized to contribute to closure of the …

The Drosophila transcription factor Grainyhead regulates several key developmental
processes. Three mammalian genes, CP2, LBP-1a and LBP-9 have been previously …

Specific inhibitors of histone deacetylase, such as trichostatin A (TSA) and trapoxin (TPX),
are potent inducers of HIV-1 transcription in latently infected T-cell lines. Activation of the …

The neural protein Fe65 possesses three putative protein-protein interaction domains: one
WW domain and two phosphotyrosine interaction/phosphotyrosine binding domains (PID1 …