Neurocritical care depends, in part, on careful patient monitoring but as yet there are little
data on what processes are the most important to monitor, how these should be monitored …

The magnitude of damage to cerebral tissues following head trauma is determined by the
primary injury, caused by the kinetic energy delivered at the time of impact, plus numerous …

Microdialysis enables the chemistry of the extracellular interstitial space to be monitored.
Use of this technique in patients with acute brain injury has increased our understanding of …

Traumatic brain injury leads to significant loss of brain volume, which continues into the
chronic stage. This can be sensitively measured using volumetric analysis of MRI. Here …

Secondary insults can adversely influence outcome following severe traumatic brain injury.
Monitoring of cerebral extracellular chemistry with microdialysis has the potential for early …

Publisher Summary This chapter highlights the controversies concerning the role of brain
inflammation elicited after brain trauma. In clinical practice, classification of primary brain …

Objective: To determine if posttraumatic nonconvulsive electrographic seizures result in long-
term brain atrophy. Methods: Prospective continuous EEG (cEEG) monitoring was done in …

Cerebral atrophy in response to traumatic brain injury is a well-documented phenomenon in
both primary investigations and review articles. Recent atrophy studies focus on exploring …

Axonal injury is believed to be a major determinant of adverse outcomes following traumatic
brain injury. However, it has been difficult to assess acutely the severity of axonal injury in …

Traumatic brain injury (TBI) research has attained renewed momentum due to the increasing
awareness of head injuries, which result in morbidity and mortality. Based on the nature of …