Metabolomics in cancer research and emerging applications in clinical oncology
Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …
Guide to metabolomics analysis: a bioinformatics workflow
Y Chen, EM Li, LY Xu - Metabolites, 2022 - mdpi.com
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The
key purpose of metabolomics is to identify the metabolites corresponding to each biological …
key purpose of metabolomics is to identify the metabolites corresponding to each biological …
[HTML][HTML] The human urine metabolome
S Bouatra, F Aziat, R Mandal, AC Guo, MR Wilson… - PloS one, 2013 - journals.plos.org
Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …
Mass spectrometric based approaches in urine metabolomics and biomarker discovery
Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
Plasma free amino acid profiling of five types of cancer patients and its application for early detection
Y Miyagi, M Higashiyama, A Gochi, M Akaike… - PloS one, 2011 - journals.plos.org
Background Recently, rapid advances have been made in metabolomics-based, easy-to-
use early cancer detection methods using blood samples. Among metabolites, profiling of …
use early cancer detection methods using blood samples. Among metabolites, profiling of …
Metabolomic approaches for detection and identification of biomarkers and altered pathways in bladder cancer
NA di Meo, D Loizzo, SD Pandolfo, R Autorino… - International Journal of …, 2022 - mdpi.com
Metabolomic analysis has proven to be a useful tool in biomarker discovery and the
molecular classification of cancers. In order to find new biomarkers, and to better understand …
molecular classification of cancers. In order to find new biomarkers, and to better understand …
Cancer metabolomic markers in urine: evidence, techniques and recommendations
SS Dinges, A Hohm, LA Vandergrift, J Nowak… - Nature reviews …, 2019 - nature.com
Urinary tests have been used as noninvasive, cost-effective tools for screening, diagnosis
and monitoring of diseases since ancient times. As we progress through the 21st century …
and monitoring of diseases since ancient times. As we progress through the 21st century …
Global urinary metabolic profiling procedures using gas chromatography–mass spectrometry
ECY Chan, KK Pasikanti, JK Nicholson - Nature protocols, 2011 - nature.com
The role of urinary metabolic profiling in systems biology research is expanding. This is
because of the use of this technology for clinical diagnostic and mechanistic studies and for …
because of the use of this technology for clinical diagnostic and mechanistic studies and for …
A support vector machine-recursive feature elimination feature selection method based on artificial contrast variables and mutual information
X Lin, F Yang, L Zhou, P Yin, H Kong, W Xing… - … of chromatography B, 2012 - Elsevier
Filtering the discriminative metabolites from high dimension metabolome data is very
important in metabolomics study. Support vector machine-recursive feature elimination …
important in metabolomics study. Support vector machine-recursive feature elimination …
Metabolic profiling regarding pathogenesis of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive, eventually fatal disease characterized
by fibrosis of the lung parenchyma and loss of lung function. IPF is believed to be caused by …
by fibrosis of the lung parenchyma and loss of lung function. IPF is believed to be caused by …