Monoligated palladium (0) species, L1Pd (0), have emerged as the most active catalytic
species in the cross-coupling cycle. Today, there are methods available to generate the …

Organoboron reagents are one of the most widely studied and applied classes of reagent
throughout organic synthesis and catalysis. Not only are these reagents integral to many of …

Fully automated synthetic chemistry would substantially change the field by providing broad
on-demand access to small molecules. However, the reactions that can be run …

Pioneering studies by Kuivila, published more than 50 years ago, suggested ipso
protonation of the boronate as the mechanism for base-catalyzed protodeboronation of …

We review here new developments in decreasing the catalyst loadings in palladium‐
catalyzed C–C bond‐formation reactions to mol ppm or mol ppb levels. This decreases the …

Boron-containing molecules have been extensively used for the purposes of chemical
sensing, biological probe development and drug discovery. Due to boron's empty p orbital, it …

Despite the widespread application of Suzuki-Miyaura cross-coupling to forge carbon-
carbon bonds, the structure of the reactive intermediates underlying the key transmetalation …

Azine‐containing biaryls are ubiquitous scaffolds in many areas of chemistry, and efficient
methods for their synthesis are continually desired. Pyridine rings are prominent amongst …

Today we are poised for a transition from the highly customized crafting of specific molecular
targets by hand to the increasingly general and automated assembly of different types of …

The Suzuki–Miyaura cross-coupling reaction has emerged as one of the most powerful
methods for the construction of carbon–carbon bonds. Though most widely utilized for the …