Means, mechanisms and consequences of adenine methylation in DNA

K Boulias, EL Greer - Nature Reviews Genetics, 2022 - nature.com
Abstract N 6-methyl-2′-deoxyadenosine (6mA or m6dA) has been reported in the DNA of
prokaryotes and eukaryotes ranging from unicellular protozoa and algae to multicellular …

Analysis of transcriptome and epitranscriptome in plants using PacBio Iso-Seq and nanopore-based direct RNA sequencing

L Zhao, H Zhang, MV Kohnen, KVSK Prasad… - Frontiers in …, 2019 - frontiersin.org
Nanopore sequencing from Oxford Nanopore Technologies (ONT) and Pacific BioSciences
(PacBio) single-molecule real-time (SMRT) long-read isoform sequencing (Iso-Seq) are …

N6-methyladenine DNA modification in the human genome

CL Xiao, S Zhu, M He, D Chen, Q Zhang, Y Chen, G Yu… - Molecular cell, 2018 - cell.com
Summary DNA N 6-methyladenine (6mA) modification is the most prevalent DNA
modification in prokaryotes, but whether it exists in human cells and whether it plays a role in …

Critical assessment of DNA adenine methylation in eukaryotes using quantitative deconvolution

Y Kong, L Cao, G Deikus, Y Fan, EA Mead, W Lai… - Science, 2022 - science.org
The discovery of N6-methyldeoxyadenine (6mA) across eukaryotes led to a search for
additional epigenetic mechanisms. However, some studies have highlighted confounding …

[HTML][HTML] iDNA6mA-PseKNC: Identifying DNA N6-methyladenosine sites by incorporating nucleotide physicochemical properties into PseKNC

P Feng, H Yang, H Ding, H Lin, W Chen, KC Chou - Genomics, 2019 - Elsevier
Abstract N 6-methyladenine (6mA) is one kind of post-replication modification (PTM or
PTRM) occurring in a wide range of DNA sequences. Accurate identification of its sites will …

Meta-4mCpred: a sequence-based meta-predictor for accurate DNA 4mC site prediction using effective feature representation

B Manavalan, S Basith, TH Shin, L Wei… - Molecular Therapy-Nucleic …, 2019 - cell.com
DNA N4-methylcytosine (4mC) is an important genetic modification and plays crucial roles in
differentiation between self and non-self DNA and in controlling DNA replication, cell cycle …

iDNA4mC: identifying DNA N4-methylcytosine sites based on nucleotide chemical properties

W Chen, H Yang, P Feng, H Ding, H Lin - Bioinformatics, 2017 - academic.oup.com
Abstract Motivation DNA N4-methylcytosine (4mC) is an epigenetic modification. The
knowledge about the distribution of 4mC is helpful for understanding its biological functions …

Meta-i6mA: an interspecies predictor for identifying DNA N6-methyladenine sites of plant genomes by exploiting informative features in an integrative machine …

MM Hasan, S Basith, MS Khatun, G Lee… - Briefings in …, 2021 - academic.oup.com
Abstract DNA N 6-methyladenine (6mA) represents important epigenetic modifications,
which are responsible for various cellular processes. The accurate identification of 6mA sites …

DNA N6-adenine methylation in Arabidopsis thaliana

Z Liang, L Shen, X Cui, S Bao, Y Geng, G Yu, F Liang… - Developmental cell, 2018 - cell.com
DNA methylation on N 6-adenine (6mA) has recently been found to be a potentially
epigenetic mark in several unicellular and multicellular eukaryotes. However, its distribution …

Identification and analysis of adenine N6-methylation sites in the rice genome

C Zhou, C Wang, H Liu, Q Zhou, Q Liu, Y Guo, T Peng… - Nature plants, 2018 - nature.com
Abstract DNA N 6-methyladenine (6mA) is a non-canonical DNA modification that is present
at low levels in different eukaryotes,,,,,,–, but its prevalence and genomic function in higher …