Programmed cell death pathways as targets for developing antifilarial drugs: Lessons from the recent findings

NC Das, P Chakraborty, S Nandy, A Dey… - Journal of Cellular …, 2023 - Wiley Online Library
More than half a century has passed since the introduction of the National Filariasis Control
Program; however, as of 2023, lymphatic filariasis (LF) still prevails globally, particularly in …

Phenolics and terpenoids; the promising new search for anthelmintics: a critical review

N Mukherjee, S Mukherjee, P Saini… - Mini reviews in …, 2016 - ingentaconnect.com
Ailments caused by helminth parasites are global causing different types of clinical
complications with permanent and long term morbidity in humans. Although huge advances …

EF24, a schistosomicidal curcumin analog: Insights from its synthesis and phenotypic, biochemical and cytotoxic activities

FR Badoco, LAL Paula, RP Orenha… - Chemico-Biological …, 2022 - Elsevier
Praziquantel (PZQ) is the only drug available for community-based control programs which
aim to reduce the prevalence and morbidity associated with schistosomiasis. Here, we …

Chitosan biopolymer functionalized gold nanoparticles with controlled cytotoxicity and improved antifilarial efficacy

P Chowdhury, B Roy, N Mukherjee… - … Composites and Hybrid …, 2018 - Springer
Ultra-high stable chitosan functionalized gold nanoparticles (GNPs) of desired biopolymeric
corona are synthesized without adding conventional hazardous reducing agents. The …

Polyphenol enriched ethanolic extract of Cajanus scarabaeoides (L.) Thouars exerts potential antifilarial activity by inducing oxidative stress and programmed cell …

AS Ray, N Joardar, S Mukherjee, CH Rahaman… - PLoS …, 2018 - journals.plos.org
Development of antifilarial drug from the natural sources is considered as one of the most
efficacious, safe, and affordable approaches. In this study, we report the antifilarial activity of …

Antifilarial activity of azadirachtin fuelled through reactive oxygen species induced apoptosis: a thorough molecular study on Setaria cervi

N Mukherjee, N Joardar, SPS Babu - Journal of helminthology, 2019 - cambridge.org
Efficacious therapeutic strategies against lymphatic filariasis are always sought after.
However, natural products are a promising resource for developing effective antifilarial …

Senna plant generates reactive oxygen species (ROS) and induces apoptosis in Hymenolepis diminuta

S Roy, N Joardar, SPS Babu, LM Lyndem - Molecular and Biochemical …, 2020 - Elsevier
Like mammalian cells, helminth parasites are equipped with an array of enzymatic anti-
oxidant system which has an adaptive strategy to cope up with several conditions of stress …

Redox regulatory circuits as targets for therapeutic intervention of bancroftian filariasis: biochemical, molecular, and pharmacological perspectives

S Mukherjee, N Joardar, SP Sinha Babu - Oxidative stress in microbial …, 2019 - Springer
Bancroftian filariasis is one of the oldest human diseases that are still posing a myriad threat
to mankind with an increasing number of new infections, morbidities, disabilities, and …

[PDF][PDF] In vivo toxicity study and antifilarial activity of four plants from Nord-Cameroon

N Dieudonné, A Mouraba, A Abakar, D Boursou… - …, 2015 - academia.edu
In vivo Toxicity Study and Antifilarial Activity of Four Plants from Nord-Cameroon Page 1
 …

[PDF][PDF] How can we avoid lymphoedema in addition to elephantiasis in Lymphatic Flariasisbecome indelible An update of treatment options in reference to a case …

KK Kaur - gsarpublishers.com
Despite the launching of the National Filarial Control Program over greater than 50% of the
century till 2024 Lymphatic Flariasis (LF) continues tobe prevalent worldwide in the tropical …