The developmental etiology and pathogenesis of Hirschsprung disease

NEB Tjaden, PA Trainor - Translational research, 2013 - Elsevier
The enteric nervous system is the part of the autonomic nervous system that directly controls
the gastrointestinal tract. Derived from a multipotent, migratory cell population called the …

Intrinsic primary afferent neuronsof the intestine

JB Furness, WAA Kunze, PP Bertrand, N Clerc… - Progress in …, 1998 - Elsevier
After a long period of inconclusive observations, the intrinsic primary afferent neurons of the
intestine have been identified. The intestine is thus equipped with two groups of afferent …

[图书][B] The enteric nervous system

JB Furness - 2008 - books.google.com
Covers all aspects of the structure, function, neurochemistry, transmitter identification and
development of the enteric nervous system This book brings together extensive knowledge …

Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS

RR Voskuhl, RS Peterson, B Song, Y Ao… - Journal of …, 2009 - Soc Neuroscience
Factors that regulate leukocyte entry and spread through CNS parenchyma during different
types of CNS insults are incompletely understood. Reactive astrocytes have been implicated …

[HTML][HTML] Fulminant jejuno-ileitis following ablation of enteric glia in adult transgenic mice

TG Bush, TC Savidge, TC Freeman, HJ Cox… - Cell, 1998 - cell.com
To investigate the roles of astroglial cells, we targeted their ablation genetically. Transgenic
mice were generated expressing herpes simplex virus thymidine kinase from the mouse …

[HTML][HTML] The endogenous cannabinoid system protects against colonic inflammation

F Massa, G Marsicano, H Hermann… - The Journal of …, 2004 - Am Soc Clin Investig
Excessive inflammatory responses can emerge as a potential danger for organisms' health.
Physiological balance between pro-and anti-inflammatory processes constitutes an …

Classes of enteric nerve cells in the guinea‐pig small intestine

SJH Brookes - The Anatomical Record: An Official Publication …, 2001 - Wiley Online Library
The guinea‐pig small intestine has been very widely used to study the physiology,
pharmacology and morphology of the enteric nervous system. It also provides an ideal …

[HTML][HTML] Gene targeting reveals a critical role for neurturin in the development and maintenance of enteric, sensory, and parasympathetic neurons

RO Heuckeroth, H Enomoto, JR Grider, JP Golden… - Neuron, 1999 - cell.com
Neurturin (NTN) is a neuronal survival factor that activates the Ret tyrosine kinase in the
presence of a GPI-linked coreceptor (either GFRα1 or GFRα2). Neurturin-deficient (NTN−/−) …

GDNF availability determines enteric neuron number by controlling precursor proliferation

S Gianino, JR Grider, J Cresswell, H Enomoto… - 2003 - journals.biologists.com
To clarify the role of Ret signaling components in enteric nervous system (ENS)
development, we evaluated ENS anatomy and intestinal contractility in mice heterozygous …

[HTML][HTML] Serotonin transporter variant drives preventable gastrointestinal abnormalities in development and function

KG Margolis, Z Li, K Stevanovic… - The Journal of …, 2016 - Am Soc Clin Investig
Autism spectrum disorder (ASD) is an increasingly common behavioral condition that
frequently presents with gastrointestinal (GI) disturbances. It is not clear, however, how gut …