DM (diabetes mellitus) is a metabolic disorder of either absolute or relative insulin
deficiency. Optimized insulin injections remain the mainstay life-sustaining therapy for …

Background: The lack of an international islet transplantation registry has prevented full
visibility of worldwide islet transplantation activity. Methods: A global online survey was …

OBJECTIVE To describe the 5-year outcomes of islet transplantation within the Swiss-
French GRAGIL Network. RESEARCH DESIGN AND METHODS Retrospective analysis of …

To describe the 10‐year outcomes of islet transplantation within the Swiss‐French GRAGIL
Network, in patients with type 1 diabetes experiencing high glucose variability associated …

Despite substantial advances in islet isolation methods and immunosuppressive protocol,
pancreatic islet cell transplantation remains an experimental procedure currently limited to …

Background. It has been suggested that the age of human organ donors might influence islet
isolation and transplantation outcome in a negative way due to a decrease of in vivo function …

The use of regional human islet cell processing centers (ICPC) supporting distant clinical
islet transplantation programs (CITP) has proven successful in recent clinical trials …

In order to make islet transplantation a therapeutic option for patients with diabetes there is
an urgent need for more efficient islet cell processing to maximize islet recovery. Improved …

Previously we demonstrated the superiority of small islets vs large islets in terms of function
and survival after transplantation, and we generated reaggregated rat islets (pseudo‐islets) …

The culture of human islets is associated with approximately 10–20% islet loss, occasionally
preventing transplantation. Preconditioning of the islets to improve postculture yields would …