The present paper review the drug–DNA interactions, their types and applications of
experimental techniques used to study interactions between DNA and small ligand …

Schiff bases have been of continued interest in coordination chemistry for a long time
because they provide new ligand platforms that make reactivity easier and their metal …

Increasing numbers of DNA structures are being revealed using biophysical, spectroscopic
and genomic methods. The diversity of transition metal complexes is also growing, as the …

The use of visible light to produce highly selective and potent drugs through photodynamic
therapy (PDT) holds much potential in the treatment of cancer. PDT agents can be designed …

Ru (phen) 32+ bound to double-helical DNA displays an increase in luminescence owing to
intercalation; emission from the met-al-to-ligand charge transfer (MLCT) excited state decays …

A novel azomethine ligand (HNAP)[HNAP= 1‐(Pyridin‐3‐yliminomethyl)‐naphthalen‐2‐ol]
and its Ag (I), Pd (II) and VO (II) chelates have been synthesized and structurally inspected …

MATERIALS AND METHODS Ruthenium Compounds. The synthesis and resolution of the
ruthenium compounds were as earlier described (Dwyer & Gyarfas, 1949; Dwyer et al …

Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …

Revised Manuscript Received December 28, 1992 abstract: Absorbance and fluorescence
methods, circular dichroism, UV melting experiments, viscosity, and competition dialysis …

Considerable attention has focused on new DNA-binding and-modifying agents, from
natural products to wholly synthetic designs, as probes of DNA structure and as po-tential …