The availability of neuroimaging technology has spurred a marked increase in the human
cognitive neuroscience literature, including the study of cognitive ageing. Although there is a …

Neuropsychological assessment has featured prominently over the past 30 years in the
characterization of dementia associated with Alzheimer disease (AD). Clinical …

Cognitive aging is a flourishing area of research. A significant amount of new data, a number
of new theoretical notions, and many new research issues have been generated in the past …

In this review we summarize the progress that has been made in the research on attentional
and executive deficits in Alzheimer's disease. Like memory, attention is now recognized as …

Provides a preliminary theoretical formulation of a threshold theory for acquired brain injury.
The theory addresses the concept of brain reserve capacity as a major factor in explaining …

Recent research on Alzheimer's disease (AD) has shown that cognitive and memory decline
in this disease is accompanied by disrupted changes in the coordination of large-scale brain …

The demographics of aging suggest a great need for the early diagnosis of dementia and
the development of preventive strategies. Neuropathology and structural MRI studies have …

Positron emission tomography (PET) was used to compare regional cerebral blood flow
(rCBF) in young (mean 26 years) and old (mean 70 years) subjects while they were …

Previous studies have led to the proposal that patients with Alzheimer's disease (AD) may
have disturbed functional connectivity between different brain regions. Furthermore, recent …

There has been increasing awareness that some slowly progressive focal cortical
syndromes can be the presenting features of Alzheimer's disease, but pathological evidence …