Liquid chromatography (LC) is an incredibly successful analytical separation tool. Its
versatility is unprecedented because of the many different separation modes …

In this tutorial, we discuss the motivations for doing two-dimensional liquid chromatography
(2D-LC) and describe the commonly used implementations of the method. We review …

In recent decades, mass spectrometry techniques, particularly when combined with
separation methods such as high-performance liquid chromatography, have become …

Flavonoids have elicited significant attention as a result of their importance in plants, their
influence on the properties of natural-product derived commodities and especially as a …

Despite progress in hardware and column technology, the complexity and heterogeneity of
many samples still pose a challenge for state-of-the-art 1D liquid chromatography (LC). As …

The interest in two-dimensional liquid chromatography (2D-LC) has been growing up since
the last decades. This promising technique appears as a relevant solution for various …

Comprehensive two-dimensional liquid chromatography (LC× LC) provides significantly
improved separation for complex real-life samples. LC× LC can be performed in one of three …

The development of analytical tools for the characterization of large biomolecules is an
emerging and rapidly evolving area. This development activity is motivated largely by the …

Online comprehensive two-dimensional liquid chromatography (online LCxLC) presents
high peak capacity compared with one-dimensional liquid chromatography, and reasonable …

A novel system for comprehensive two-dimensional liquid chromatography coupled to a
triple quadrupole mass spectrometer is described for the analysis of wine components. The …