The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Diseases caused by fungi can occur in healthy people, but immunocompromised patients
are the major risk group for invasive fungal infections. Cases of fungal resistance and the …

The development of biocompatible polymeric nanoparticles has become an important
strategy for optimizing the therapeutic efficacy of many classical drugs, as it may expand …

The release of extracellular vesicles (EVs) by fungi is a fundamental cellular process. EVs
carry several biomolecules, including pigments, proteins, enzymes, lipids, nucleic acids, and …

Extracellular vesicles (EVs) are a heterogeneous group of lipid membrane-enclosed
compartments that contain different biomolecules and are released by almost all living cells …

Paracoccidioidomycosis is a neglected disease that causes economic and social impacts,
mainly affecting people of certain social segments, such as rural workers. The limitations of …

ABSTRACT Vaccination with peptide 10 (P10), derived from the Paracoccidioides
brasiliensis glycoprotein 43 (gp43), induces a Th1 response that protects mice in an …

Background Paracoccidioides brasiliensis and P. lutzii cause paracoccidioidomycosis
(PCM). P. brasiliensis main diagnostic antigen is glycoprotein gp43, and its peptide …

Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America. It is
becoming globally relevant, as increasing numbers of cases have been detected in …

Human fungal infections remain a major challenge in medicine. Only a limited number of
antifungal drugs are available, which are often related to severe adverse effects. In addition …