Toxicogenomics enjoyed considerable attention as a ground-breaking addition to
conventional toxicology assays at its inception. However, the pace at which toxicogenomics …

Global measurement of proteins and their many attributes in tissues and biofluids defines
the field of proteomics. Toxicoproteomics, as part of the larger field of toxicogenomics, seeks …

Over the last decade, the introduction of microarray technology has had a profound impact
on gene expression research. The publication of studies with dissimilar or altogether …

Over the last decade, the introduction of microarray technology has had a profound impact
on gene expression research. The publication of studies with dissimilar or altogether …

Abstract The Comparative Toxicogenomics Database (CTD) is a curated database that
promotes understanding about the effects of environmental chemicals on human health …

To validate and extend the findings of the MicroArray Quality Control (MAQC) project, a
biologically relevant toxicogenomics data set was generated using 36 RNA samples from …

Biofuels derived from algal lipids represent an opportunity to dramatically impact the global
energy demand for transportation fuels. Systems biology analyses of oleaginous algae …

Direct comparison of the hepatoma cell lines HepG2 and HepaRG has previously been
performed by only evaluating a limited set of genes or proteins. In this study, we examined …

Selecting a model in predictive toxicology often involves a trade-off between prediction
performance and explainability: should we sacrifice the model performance to gain …

It is widely recognized that either predicting or determining the absorption, distribution,
metabolism, excretion and toxicity (ADME/Tox) properties of molecules helps to prevent the …