[PDF][PDF] Phospholipases A2 from viperidae snake venoms: how do they induce skeletal muscle damage?

B Lomonte, JM Gutiérrez - 2011 - researchgate.net
Abstract Phospholipases A2 (PLA2s) are abundant components in snake venoms, which
play important toxic roles. This review focuses on group II PLA2s endowed with myotoxic …

Inflammatory Effects of Bothrops Phospholipases A2: Mechanisms Involved in Biosynthesis of Lipid Mediators and Lipid Accumulation

V Moreira, E Leiguez, PM Janovits, R Maia-Marques… - Toxins, 2021 - mdpi.com
Phospholipases A2s (PLA2s) constitute one of the major protein groups present in the
venoms of viperid and crotalid snakes. Snake venom PLA2s (svPLA2s) exhibit a remarkable …

[HTML][HTML] Comparative analysis of newborn and adult Bothrops jararaca snake venoms

TC Antunes, KM Yamashita, KC Barbaro, M Saiki… - Toxicon, 2010 - Elsevier
Different clinical manifestations have been reported to occur in patients bitten by newborn
and adult Bothrops jararaca snakes. Herein, we studied the chemical composition and …

Myotoxic phospholipases A2 isolated from Bothrops brazili snake venom and synthetic peptides derived from their C-terminal region: cytotoxic effect on microorganism …

TR Costa, DL Menaldo, CZ Oliveira, NA Santos-Filho… - peptides, 2008 - Elsevier
This paper reports the purification and biochemical/pharmacological characterization of two
myotoxic phospholipases A2 (PLA2s) from Bothrops brazili venom, a native snake from …

Snake venom proteome of Protobothrops mucrosquamatus in Taiwan: Delaying venom-induced lethality in a rodent model by inhibition of phospholipase A2 activity …

CC Liu, CJ Wu, YC Hsiao, YH Yang, KL Liu… - Journal of …, 2021 - Elsevier
Protobothrops mucrosquamatus, also known as the brown spotted pit viper or Taiwanese
habu, is a medically significant venomous snake in Taiwan, especially in the northern area …

Isolation of an acidic phospholipase A2 from the venom of the snake Bothrops asper of Costa Rica: biochemical and toxicological characterization

J Fernández, JM Gutiérrez, Y Angulo, L Sanz, P Juárez… - Biochimie, 2010 - Elsevier
Phospholipases A2 (PLA2) are major components of snake venoms, exerting a variety of
relevant toxic actions such as neurotoxicity and myotoxicity, among others. Since the …

Molecular docking studies and anti-enzymatic activities of Thai mango seed kernel extract against snake venoms

J Leanpolchareanchai, P Pithayanukul, R Bavovada… - Molecules, 2009 - mdpi.com
The ethanolic extract from seed kernels of Thai mango (MSKE)(Mangifera indica L.
cv.'Fahlun')(Anacardiaceae) and its major phenolic principle (pentagalloyl glucopyranose) …

A new acidic myotoxic, anti-platelet and prostaglandin I2 inductor phospholipase A2 isolated from Bothrops moojeni snake venom

NA Santos-Filho, LB Silveira, CZ Oliveira… - Toxicon, 2008 - Elsevier
Phospholipase A2 (PLA2, EC 3.1. 1.4), a major component of snake venoms, specifically
catalyzes the hydrolysis of fatty acid ester bonds at position 2 of 1, 2-diacyl-sn-3 …

Snake venoms: attractive antimicrobial proteinaceous compounds for therapeutic purposes

NG de Oliveira Junior, MH e Silva Cardoso… - Cellular and molecular …, 2013 - Springer
Gram-positive and-negative bacteria are dangerous pathogens that may cause human
infection diseases, especially due to the increasingly high prevalence of antibiotic …

Purification, Characterization and Evaluation of the Antitumoral Activity of a Phospholipase A2 from the Snake Bothrops moojeni

BEF Frihling, APA Boleti, CFR de Oliveira… - Pharmaceuticals, 2022 - mdpi.com
Nature presents a wide range of biomolecules with pharmacological potential, including
venomous animal proteins. Among the protein components from snake venoms …