Androgen effects on the adrenergic system of the vascular, airway, and cardiac myocytes and their relevance in pathological processes
A Carbajal-García, J Reyes-García… - International Journal of …, 2020 - Wiley Online Library
Introduction. Androgen signaling comprises nongenomic and genomic pathways.
Nongenomic actions are not related to the binding of the androgen receptor (AR) and occur …
Nongenomic actions are not related to the binding of the androgen receptor (AR) and occur …
Beyond prostate cancer: An androgen receptor splice variant expression in multiple malignancies, non-cancer pathologies, and development
Multiple studies have demonstrated the importance of androgen receptor (AR) splice
variants (SVs) in the progression of prostate cancer to the castration-resistant phenotype …
variants (SVs) in the progression of prostate cancer to the castration-resistant phenotype …
Identification of androgen receptor splice variant transcripts in breast cancer cell lines and human tissues
The androgen receptor (AR) is widely expressed in human tissues and has biological
function in many male and female organs. In particular, the AR plays a critical role in the …
function in many male and female organs. In particular, the AR plays a critical role in the …
Activation of GPER-1 estradiol receptor downregulates production of testosterone in isolated rat Leydig cells and adult human testis
L Vaucher, MG Funaro, A Mehta, A Mielnik, A Bolyakov… - PloS one, 2014 - journals.plos.org
Purpose Estradiol (E2) modulates testicular functions including steroidogenesis, but the
mechanisms of E2 signaling in human testis are poorly understood. GPER-1 (GPR30), a G …
mechanisms of E2 signaling in human testis are poorly understood. GPER-1 (GPR30), a G …
Androgen receptor and its splicing variant 7 expression in peripheral blood mononuclear cells and in circulating tumor cells in metastatic castration-resistant prostate …
M Marín-Aguilera, N Jiménez, Ò Reig, R Montalbo… - Cells, 2020 - mdpi.com
Androgen receptor (AR) signaling remains crucial in castration-resistant prostate cancer
(CRPC). Since it is also essential in immune cells, we studied whether the expression of AR …
(CRPC). Since it is also essential in immune cells, we studied whether the expression of AR …
Molecular origin, expression regulation, and biological function of androgen receptor splicing variant 7 in prostate cancer
Y Chen, T Lan - Urologia Internationalis, 2021 - karger.com
The problem of resistance to therapy in prostate cancer (PCa) is multifaceted. Key
determinants of drug resistance include tumor burden and growth kinetics, tumor …
determinants of drug resistance include tumor burden and growth kinetics, tumor …
Fish granulocytes express a constitutively active androgen receptor variant
M Sánchez-Hernández, M Arizcun… - Developmental & …, 2014 - Elsevier
In humans, alternative splicing of androgen receptor (AR) is usually involved in some
diseases. However, our knowledge about the presence of AR variants in other species and …
diseases. However, our knowledge about the presence of AR variants in other species and …
Characterization and expression of androgen receptors in olive flounder
Y Zou, L Peng, S Weng, D Liang, Z Fan, Z Wu, X Tan… - Gene, 2019 - Elsevier
Androgens are critical hormones that regulate sex differentiation, sexual maturation, and
spermatogenesis in vertebrates, which is mainly mediated by androgen receptors (ARs) …
spermatogenesis in vertebrates, which is mainly mediated by androgen receptors (ARs) …
Animal models of transgenerational epigenetic effects
CS Rosenfeld - Transgenerational epigenetics, 2014 - Elsevier
The realization that epigenetic changes caused by extrinsic factors can be transmitted from
an exposed founder to its progeny and subsequent generations in a wide range of taxons …
an exposed founder to its progeny and subsequent generations in a wide range of taxons …
Effekte pränataler Dexamethasonapplikation auf ausgewählte Parameter der männlichen Reproduktion in nachfolgenden Generationen beim Weißbüschelaffen …
RFW Utsch - 2021 - ul.qucosa.de
Abstract (DE) Einleitung: Der Einfluss von Stress während der Schwangerschaft auf den
Fetus lässt sich auch postnatal bis in das Erwachsenenalter und teilweise sogar bis in …
Fetus lässt sich auch postnatal bis in das Erwachsenenalter und teilweise sogar bis in …