A bundle of mechanisms: inner-ear hair-cell mechanotransduction

DÓ Maoiléidigh, AJ Ricci - Trends in neurosciences, 2019 - cell.com
In the inner ear, the deflection of hair bundles, the sensory organelles of hair cells, activates
mechanically-gated channels (MGCs). Hair bundles monitor orientation of the head, its …

Neuromorphic acoustic sensing using an adaptive microelectromechanical cochlea with integrated feedback

C Lenk, P Hövel, K Ved, S Durstewitz, T Meurer… - Nature …, 2023 - nature.com
Many speech processing systems struggle in conditions with low signal-to-noise ratios and
in changing acoustic environments. Adaptation at the transduction level with integrated …

Symmetry, thermodynamics, and topology in active matter

MJ Bowick, N Fakhri, MC Marchetti, S Ramaswamy - Physical Review X, 2022 - APS
The name active matter refers to any collection of entities that individually use free energy to
generate their own motion and forces. Through interactions, active particles spontaneously …

Mechanical frequency tuning by sensory hair cells, the receptors and amplifiers of the inner ear

P Martin, AJ Hudspeth - Annual Review of Condensed Matter …, 2021 - annualreviews.org
We recognize sounds by analyzing their frequency content. Different frequency components
evoke distinct mechanical waves that each travel within the hearing organ, or cochlea, to a …

A bifurcation integrates information from many noisy ion channels and allows for millikelvin thermal sensitivity in the snake pit organ

IR Graf, BB Machta - Biophysical Journal, 2024 - cell.com
Tuesday, February 13, 2024 325a can have an extremely sharp dependence on
temperature, naturally accounting for the thousand-fold amplification. Furthermore, close to …

Dimensions of a living cochlear hair bundle

KK Miller, P Atkinson, KR Mendoza… - Frontiers in Cell and …, 2021 - frontiersin.org
The hair bundle is the mechanosensory organelle of hair cells that detects mechanical
stimuli caused by sounds, head motions, and fluid flows. Each hair bundle is an assembly of …

A novel MEMS sensor concept to improve signal-to-noise ratios

N Lam, S Hayashi, S Gutschmidt - International Journal of Non-Linear …, 2022 - Elsevier
Dynamic measuring concepts of sensors use a variety of different metrics. Some monitor the
amplitude and/or phase, while others track resonance frequency or stability thresholds …

Chaotic dynamics enhance the sensitivity of inner ear hair cells

J Faber, D Bozovic - Scientific reports, 2019 - nature.com
Hair cells of the auditory and vestibular systems are capable of detecting sounds that induce
sub-nanometer vibrations of the hair bundle, below the stochastic noise levels of the …

Self-tuned criticality: Controlling a neuron near its bifurcation point via temporal correlations

JT Moraes, EJA Trejo, S Camargo, SC Ferreira… - Physical Review E, 2023 - APS
Previous work showed that the collective activity of large neuronal networks can be tamed to
remain near its critical point by a feedback control that maximizes the temporal correlations …

The Cochlea

LP Rybak - Inflammatory mechanisms in mediating hearing loss, 2018 - Springer
The mammalian cochlea is an intricately designed organ that is exquisitely sensitive to
sound. It possesses unique physical and chemical properties that permit this organ to …