Reactive oxygen species and gastric carcinogenesis: The complex interaction between Helicobacter pylori and host

S Wu, Y Chen, Z Chen, F Wei, Q Zhou, P Li… - Helicobacter, 2023 - Wiley Online Library
Helicobacter pylori (H. pylori) is a highly successful human pathogen that colonizes stomach
in around 50% of the global population. The colonization of bacterium induces an …

Oxidative and nitrosative stress defences of Helicobacter and Campylobacter species that counteract mammalian immunity

A Flint, A Stintzi, LM Saraiva - FEMS Microbiology Reviews, 2016 - academic.oup.com
Helicobacter and Campylobacter species are Gram-negative microaerophilic host-
associated heterotrophic bacteria that invade the digestive tract of humans and animals …

Insights into the Orchestration of Gene Transcription Regulators in Helicobacter pylori

A Vannini, D Roncarati, F D'Agostino… - International Journal of …, 2022 - mdpi.com
Bacterial pathogens employ a general strategy to overcome host defenses by coordinating
the virulence gene expression using dedicated regulatory systems that could raise intricate …

Expanding the role of FurA as essential global regulator in cyanobacteria

A Gonzalez, MT Bes, ML Peleato, MF Fillat - PloS one, 2016 - journals.plos.org
In the nitrogen-fixing heterocyst-forming cyanobacterium Anabaena sp. PCC 7120, the ferric
uptake regulator FurA plays a global regulatory role. Failures to eliminate wild-type copies of …

Comprehensive mapping of the Helicobacter pylori NikR regulon provides new insights in bacterial nickel responses

A Vannini, E Pinatel, PE Costantini, S Pelliciari… - Scientific reports, 2017 - nature.com
Nickel homeostasis is important for pathogenic and ureolytic bacteria, which use this metal
ion as enzymatic cofactor. For example, in the human pathogen Helicobacter pylori an …

Redox-based transcriptional regulation in prokaryotes: revisiting model mechanisms

E Sevilla, MT Bes, A Gonzalez, ML Peleato… - Antioxidants & redox …, 2019 - liebertpub.com
Significance: The successful adaptation of microorganisms to ever-changing environments
depends, to a great extent, on their ability to maintain redox homeostasis. To effectively …

Insight into the essential role of the Helicobacter pylori HP1043 orphan response regulator: genome-wide identification and characterization of the DNA-binding sites

S Pelliciari, E Pinatel, A Vannini, C Peano, S Puccio… - Scientific reports, 2017 - nature.com
Many bacterial regulatory genes appear to be dispensable, as they can be deleted from the
genome without loss of bacterial functionalities. In Helicobacter pylori, the hp1043 gene …

HP1021 is a redox switch protein identified in Helicobacter pylori

P Szczepanowski, M Noszka… - Nucleic Acids …, 2021 - academic.oup.com
Helicobacter pylori is a gram-negative, microaerophilic, pathogenic bacterium and a
widespread colonizer of humans. H. pylori has developed mechanisms that enable it to …

BlsA integrates light and temperature signals into iron metabolism through Fur in the human pathogen Acinetobacter baumannii

MR Tuttobene, P Cribb, MA Mussi - Scientific reports, 2018 - nature.com
Light modulates global features of the important human pathogen Acinetobacter baumannii
lifestyle including metabolism, tolerance to antibiotics and virulence, most of which depend …

The Role of Fur in the Transcriptional and Iron Homeostatic Response of Enterococcus faecalis

M Latorre, D Quenti, D Travisany, KV Singh… - Frontiers in …, 2018 - frontiersin.org
The ferric uptake regulator (Fur) plays a major role in controlling the expression of iron
homeostasis genes in bacterial organisms. In this work, we fully characterized the capacity …