The three subsets of human monocytes, classical, intermediate, and nonclassical, show
phenotypic heterogeneity, particularly in their expression of CD14 and CD16. This has …

Purpose The COVID-19 pandemic caused by the novel Severe Acute Respiratory Syndrome
Corona Virus 2 (SARS-CoV-2) has put the world in a medical crisis for the past three years; …

Innate immune cells play essential roles in modulating both immune defense and
inflammation by expressing a diverse array of cytokines and inflammatory mediators …

Severe COVID-19 elicits excessive inflammation mediated by innate immune cells like
monocytes. Recent evidence reveals extensive epigenetic changes in monocytes during …

Sepsis-induced acute lung injury (ALI), characterized by severe hypoxemia and pulmonary
leakage, remains a leading cause of mortality in intensive care units. The exacerbation of …

Abstract Deep Generative Models (DGMs) are becoming instrumental for inferring
probability distributions inherent to complex processes, such as most questions in …

Despite extensive studies on the effects of SARS-CoV-2 infection, there is still a lack of
understanding of the downstream epigenetic and regulatory alterations in infected cells. In …

Myeloid cells play a vital role in innate immune responses as they recognize and
phagocytose pathogens like viruses, present antigens, produce cytokines, recruit other …

Blood transcriptional profiling is a powerful tool to evaluate immune responses to infection;
however, blood collection via traditional phlebotomy remains a barrier to precise …

All living organisms must maintain homeostasis to survive, reproduce, and pass their traits
on to the next generation. If homeostasis is not maintained, it can result in various diseases …