Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review

L Sharp, J Little - American journal of epidemiology, 2004 - academic.oup.com
Epidemiologic and mechanistic evidence suggests that folate is involved in colorectal
neoplasia. Some polymorphic genes involved in folate metabolism …

Genetic polymorphisms of methylenetetrahydrofolate reductase and colorectal cancer and adenoma

S Kono, K Chen - Cancer science, 2005 - Wiley Online Library
Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme regulating folate
metabolism, which affects DNA methylation and synthesis. Two functional, common …

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer: The Fukuoka Colorectal Cancer Study

G Yin, S Kono, K Toyomura, T Hagiwara… - Cancer …, 2004 - Wiley Online Library
Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme regulating folate
metabolism, which affects DNA synthesis and methylation. This study investigated the …

La reacción en cadena de la polimerasa a dos décadas de su invención

IP Rodríguez Sánchez, HA Barrera Saldaña - Ciencia uanl, 2004 - eprints.uanl.mx
La PCR, técnica inventada por Kary B. Mullis en 1983, emplea un par de oligonucleótidos
para delimitar una región de interés y una polimerasa para extenderlos, utilizando ambas …

Folate Intake, MTHFR Polymorphisms, and the Risk of Colorectal Cancer: A Systematic Review and Meta‐Analysis

DA Kennedy, SJ Stern, I Matok… - Journal of cancer …, 2012 - Wiley Online Library
Background. The objective was to determine whether relationships exist between the
methylene‐tetrahydrofolate reductase (MTHFR) polymorphisms and risk of colorectal cancer …

Nonsynonymous polymorphisms in genes in the one-carbon metabolism pathway and associations with colorectal cancer

A Koushik, P Kraft, CS Fuchs, SE Hankinson… - … Biomarkers & Prevention, 2006 - AACR
Abstract The Ala222Val single nucleotide polymorphism (SNP) in the gene for 5, 10-
methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in one-carbon metabolism …

[HTML][HTML] Risk of colorectal cancer associated with the C677T polymorphism in 5, 10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake …

CS Guerreiro, B Carmona, S Gonçalves… - The American journal of …, 2008 - Elsevier
Background: Polymorphisms located in genes involved in the metabolism of folate and some
methyl-related nutrients are implicated in colorectal cancer (CRC). Objective: We evaluated …

Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms in patients with small cell and non-small cell lung cancer

K Siemianowicz, J Gminski, W Garczorz… - Oncology …, 2003 - spandidos-publications.com
Two mutations of methylenetetrahydrofolate reductase (MTHFR) gene (C677T and A1298C)
may lead to a decreased activity of the enzyme. These mutations may change a risk of some …

Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population

LH Cui, MH Shin, SS Kweon, HN Kim, HR Song… - BMC cancer, 2010 - Springer
Background This study was designed to investigate an association between the
methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and the risk of gastric …

Adenovirus 5 produces obesity and adverse metabolic, morphological, and functional changes in the long term in animals fed a balanced diet or a high-fat diet: A …

DA Montes-Galindo, AC Espiritu-Mojarro, V Melnikov… - Archives of …, 2019 - Springer
Abstract Adenovirus 5 (Ad-5) infection is a common cause of acute respiratory infections and
the main vector used in gene therapy. There are few studies on the relationship of Ad-5 to …