Mesenchymal stromal cells as conductors of adipose tissue remodeling
J Cannavino, RK Gupta - Genes & Development, 2023 - genesdev.cshlp.org
Adipose tissue exhibits a remarkable capacity to expand, contract, and remodel in response
to changes in physiological and environmental conditions. Here, we describe recent …
to changes in physiological and environmental conditions. Here, we describe recent …
Circadian mechanisms in adipose tissue bioenergetics and plasticity
The circadian clock plays an essential role in coordinating feeding and metabolic rhythms
with the light/dark cycle. Disruption of clocks is associated with increased adiposity and …
with the light/dark cycle. Disruption of clocks is associated with increased adiposity and …
Single-cell analysis reveals a subpopulation of adipose progenitor cells that impairs glucose homeostasis
Adipose progenitor cells (APCs) are heterogeneous stromal cells and help to maintain
metabolic homeostasis. However, the influence of obesity on human APC heterogeneity and …
metabolic homeostasis. However, the influence of obesity on human APC heterogeneity and …
Adipose tissue as a linchpin of organismal ageing
TT Nguyen, S Corvera - Nature Metabolism, 2024 - nature.com
Ageing is a conserved biological process, modulated by intrinsic and extrinsic factors, that
leads to changes in life expectancy. In humans, ageing is characterized by greatly increased …
leads to changes in life expectancy. In humans, ageing is characterized by greatly increased …
Perirenal adipose tissue contains a subpopulation of cold-inducible adipocytes derived from brown-to-white conversion
Perirenal adipose tissue (PRAT) is a unique visceral depot that contains a mixture of brown
and white adipocytes. The origin and plasticity of such cellular heterogeneity remains …
and white adipocytes. The origin and plasticity of such cellular heterogeneity remains …
Chronic β3‐AR stimulation activates distinct thermogenic mechanisms in brown and white adipose tissue and improves systemic metabolism in aged mice
D Natarajan, B Plakkot, K Tiwari, S Ekambaram… - Aging …, 2024 - Wiley Online Library
Adipose thermogenesis has been actively investigated as a therapeutic target for improving
metabolic dysfunction in obesity. However, its applicability to middle‐aged and older …
metabolic dysfunction in obesity. However, its applicability to middle‐aged and older …
Becoming less beige with age
Adipocytes: Becoming less beige with age | eLife Skip to Content eLife logo eLife home page
Menu Home Magazine Community About Search Alerts Submit your research Search by …
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Decoding temporal thermogenesis: coregulator selectivity and transcriptional control in brown and beige adipocytes
YG Jeon, SW Kim, JB Kim - Adipocyte, 2024 - Taylor & Francis
In mammals, brown adipose tissue (BAT) and beige adipocytes in white adipose tissue
(WAT) play pivotal roles in maintaining body temperature and energy metabolism. In mice …
(WAT) play pivotal roles in maintaining body temperature and energy metabolism. In mice …
The effects of ghrelin and LEAP-2 in energy homeostasis are modulated by thermoneutrality, high-fat diet and aging
S Casado, M Varela-Miguéns, T de Oliveira Diz… - Journal of …, 2024 - Springer
Purpose Liver-expressed antimicrobial peptide 2 (LEAP-2) has been recently identified as
the endogenous non-competitive allosteric antagonist of the growth hormone secretagogue …
the endogenous non-competitive allosteric antagonist of the growth hormone secretagogue …
[HTML][HTML] Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity
J So, O Strobel, J Wann, K Kim, A Paul, DJ Acri… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Single nucleus RNA sequencing (snRNA-seq), an alternative to single cell RNA sequencing
(scRNA-seq), encounters technical challenges in obtaining high-quality nuclei and RNA …
(scRNA-seq), encounters technical challenges in obtaining high-quality nuclei and RNA …