La enseñanza de la investigación debe abarcar todos los aspectos de su proceso,
involucrando los estudios piloto. En la investigación biomédica, el primer paso en la …

We describe a framework for defining pilot and feasibility studies focusing on studies
conducted in preparation for a randomised controlled trial. To develop the framework, we …

Background Implementation trials aim to test the effects of implementation strategies on the
adoption, integration or uptake of an evidence-based intervention within organisations or …

Purpose Venous thromboembolism (VTE) is common in patients with cancer. Long-term
daily subcutaneous low molecular weight heparin has been standard treatment for such …

Background: Pilot studies test the feasibility of methods and procedures to be used in larger-
scale studies. Although numerous articles describe guidelines for the conduct of pilot …

Aim: To evaluate the efficacy of autologous adipose-derived mesenchymal stem cell
(ADMSC) therapy on pain, function and disease modification in knee osteoarthritis. Methods …

Deep learning (DL) algorithms have rapidly become a robust tool for analyzing medical
images. They have been used extensively for medical image segmentation as the first and …

Academic research plays a key role in identifying new drug targets, including understanding
target biology and links between targets and disease states. To lead to new drugs, however …

Agriculture, particularly small-scale farming, is both a contributor to greenhouse gas (GHG)
emissions and a victim of the effects of climate change. Climate-smart agriculture (CSA) …

Background The current CONSORT guidelines for reporting pilot trials do not recommend
hypothesis testing of clinical outcomes on the basis that a pilot trial is under-powered to …